the esterification of p-aminobenzoic acid with ethanol. The percent yield of crude product was determined to be 21% and the melting point was recorded at 86.2°C ± 0.2°C‚ with a 6.3% error from 92°C‚ the literature melting point of pure benzocaine. The crude product was then recrystallized to improve the purity of benzocaine and 57.4% was recovered. The new melting point range was measured at 89.1°C ± 0.3°C‚ which has a 3.15% error. The infrared spectrum of the recrystallized product was measured
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1: MELTING POINT AND BOILING POINTS OF ORGANIC COMPOUNDS ABSTRACT The properties of organic compounds depend on their chemical structures. Intermolecular forces of attraction affect physical properties such as melting and boiling point. Through the Thomas Hoover apparatus‚ the melting point of 8 test compounds was determined. Salicylic acid exhibited the highest melting point while naphthalene‚ the lowest. The stronger the intermolecular forces of attraction‚ the higher the melting point. Boiling
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Synthesis of Aspirin and Oil of Wintergreen INTRODUCTION: Synthesis and use of organic compounds is an extremely important area of modern chemistry. Approximately half of all chemists work with organic chemicals. In everyday life‚ many if not most of the chemicals you come in contact with are organic chemicals. Examples include drugs‚ synthetic fabrics‚ paints‚ plastics‚ etc. Synthesis of Aspirin and Methyl Salicylate. The two compounds we will be preparing‚ aspirin (acetylsalicylic acid) and oil
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The Purity and Purification of Solids Melting Point Lab Introduction: The point of this lab was to determine the eutectic point for the naphthalene biphenyl mixture‚ as well as determining the melting point of an unknown substance by comparing it with two known samples. Melting point is a temperature in which a substance changes from solid state to liquid state. Melting points are used to determine whether the given substance is pure or not. Substances that melt sharply‚ less than 1-2°C indicates
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Once the aspirin is prepared‚ it is isolated from the reaction solution and then it is purified. The aspirin is insoluble in cold water‚ and it is isolated by filtering the chilled reaction solution. Purification is essential to remove any unreacted salicylic acid and acetic anhydride as well as the acetic acid product and phosphoric acid. Acetic anhydride is caused to decompose by the addition of water once the formation of aspirin is complete. C4H6O3 (Acetic anhydride) + H2O (Water) ------------------------->
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Preparation of an Ester Acetylsalicylic Acid (Aspirin) OBJECTIVE: To become familiar with the techniques and principle of esterification. DISCUSSION: Aspirin is a drug widely used as an antipyretic agent (to reduce fever)‚ as an analgesic agent (to reduce pain)‚ and/or as an anti-inflammatory agent (to reduce redness‚ heat or swelling in tissues). Chemically‚ aspirin is an ester. Esters are the products of reaction of acids with alcohols‚ as shown in the following equation using
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in the first part of the lab; when we have to produce crystals of aspirin. Analysis is the separation‚ identification‚ and quantification of the chemical components of natural and artificial materials. This concept is used throughout the lab when we are analyzing different reactions that are happing during the duration of the lab. The goal of this lab is to synthesize a sample of acetylsalicylic acid‚ otherwise known as aspirin. This is the most important goal of the lab. This‚ however‚ has side
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Introduction: The purpose of this lab was to learn how to use salicylic acid to make aspirin. Aspirin is the most widely used over-the-counter drug in the world. The average tablet contains about 325 milligrams of acetylsalicylic acid with an inert binding material such as starch. Aspirin is used to relieve pain‚ reduce inflammation‚ and lower fever. Aspirin originally was derived by boiling the bark of the white willow tree. Although the salicin in willow bark has analgesic properties‚ purified
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Lab Report Synthesis and Characterization of Aspirin (Acetylsalicylic Acid) The Synthesis and Characterization of Aspirin (Acetylsalicylic Acid). Summary: In this experiment‚ we produced 4.21 g of acetylsalicylic acid. Our theoretical yield was calculated to be 5.22 g. Therefore our % yield was determined to be 80.6%. The experimental boiling point range of acetylsalicylic acid was found to be 130-132° C. The true melting point of acetylsalicylic acid is 135° C‚ therefore our percent
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Abstract For the amount of aspirin in a commercial tablet to be determined‚ different solutions of acetylsalicylic acid mixed with NaOH were created at different concentrations. All the different solutions were then analysed using Novaspec photometer‚ which allowed for a graph to be created and a line of best fit to be made. The amount of aspirin in a commercial tablet was found to be 350mg. Introduction The molecular formula for aspirin‚ also known as acetylsalicylic acid‚ is C9H8O4. It is most
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