For the amount of aspirin in a commercial tablet to be determined, different solutions of acetylsalicylic acid mixed with NaOH were created at different concentrations. All the different solutions were then analysed using Novaspec photometer, which allowed for a graph to be created and a line of best fit to be made. The amount of aspirin in a commercial tablet was found to be 350mg.
Introduction
The molecular formula for aspirin, also known as acetylsalicylic acid, is C9H8O4. It is most commonly used as an anti-inflammatory, fever and painkilling drug, and was originally discovered in the bark of the willow tree in 1763 by Edward Stone (Monash University, Department of Epidemiology and Preventive Medicine, 2010). Aspirin, also known as …show more content…
0.4833 x 2 = 10 x C2
0.9666 = 10 x C2
0.966610 = 0.09666g per 100ml
A graph was drawn by plotting the absorbance of all the solutions measured, against their concentration. From this graph, the concentration of aspirin in the tablet solution was found to be 0.3500. This was calculated by drawing a straight line from its absorbance of 0.100 to the point where it crosses the drawn line of best fit. The point at which they met was read to be 0.3500, which gave the concentration of the tablet to be 0.35g per 100ml.
The mass of the aspirin in the tablet was found to be 350mg using the following calculations:-
It was found that the aspirin concentration of the tablet was 0.35g per 100ml. The volume in which the tablet was dissolved was 100ml, so the mass of the tablet used was 0.35g.
0.35g x 1000= 350mg
Table 2: The mass of aspirin in the tablet found by the whole