"Enzyme Inhibitor" Essays and Research Papers

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Enzyme Inhibitor

………………………………………………………………………………..9 Properties of Enzymes and Competitive Inhibitors. Abstract: Properties of enzymes were found in this experiment and some other factors, which affect enzyme activity. Enzymes are catalyst; they catalyze very specific reactions. Results relating to the active site of specific enzymes played a big role while performing this experiment. The purpose of this experiment was to fin how inhibitors affect enzyme’s activity by competing for the active site against...

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Reaction Rate and Rate Law

CH3 NC(g) −→ CH3 CN(g) are 4.0 × 1013 s−1 and 272 kJ/mole, respectively. Calculate the values of ∆S ◦‡ , ∆H ◦‡ , and ∆G◦‡ at 300 K. 7. [20 points] An enzyme-catalyzed reaction (KM = 2.7 × 10−3 M) is inhibited by a competitive inhibitor I (KI = 3.1 × 10−5 M). Suppose that the substrate concentration is 3.6 × 10−4 M. How much of an inhibitor is needed for 65% inhibition? How much does the substrate concentration have to be increased to reduce the inhibition to 25%? Constants R = 8.314 J-K−1...

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lead compounds. Virtual screening (VS) is a computational technique used in drug discovery to search libraries of small molecules in order to identify those structures which are most likely to bind to a drug target, typically a protein receptor or enzyme. Virtual screening has been defined as the "automatically evaluating very large libraries of compounds" using computer programs. As this definition suggests, VS has largely been a numbers game focusing on how the enormous chemical space of over 1060...

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Enzyme Substrate

The bonding of an enzyme to its substrate forms an enzyme-substrate complex. The catalytic action of the enzyme converts its substrate into the product or products of the reaction. Each reaction is extremely specific, distinguishing between closely related compounds, including isomers. For example, the enzyme sucrase will only act on sucrose and will not bind to any other disaccharide. The molecular recognition of enzymes is due to the fact that they are proteins, which are defined as being macromolecules...

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May 1, 2013 Enzymes as Drug Targets Enzymes are defined as any of numerous proteins produced in living cells that accelerate or catalyze the metabolic processes of an organism. Enzymes are usually very selective in the molecules that they act upon, called substrates, often reacting with only a single substrate. The substrate binds to the enzyme at a location called the active site just before the reaction catalyzed by the enzyme takes place. Enzymes can speed up chemical reactions by up to...

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Enzyme Structure and Functions:

ENZYME STRUCTURE AND FUNCTIONS: Enzymes are biological catalysts. They increase the rate of reactions by a factor of between 106 to 1012 times, allowing the chemical reactions that make life possible to take place at normal temperatures Definition of enzyme: A protein with catalytic properties due to its power of specific activation is defined as an enzyme. STRUCTURE Enzymes are proteins their function depends on its complexity. The reaction takes place in a small part of the enzyme...

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Enzyme and Heavy Metals

 ENZYME COFACTORS AND INHIBITORS 1. DESCRIBE THE GENERAL ROLE OF COFACTORS IN ENZYME ACTIVITY. Some chemicals enhance an enzyme’s activity, which is what cofactors function to do. They are a non-protein component of an enzyme and may be organic molecules (called coenzymes) or inorganic ions. 2. (A) NAME FOUR HEAVY METALS THAT ARE TOXIC TO HUMANS. Four heavy metals that are toxic to humans are: 1. Cadmium (Cd) 2. Lead (Pb) 3. Mercury (Hg) 4. Arsenic (As) (B) EXPLAIN IN GENERAL TERMS WHY...

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Enzyme Activity Lab

Title: Enzyme Activity Lab Purpose: To measure the rate of enzyme activity from a tissue abstract and experiment with different factors, such as the enzyme solution and the substrate with different hydrogen peroxide percentages and temperature, that affect enzyme activity. Hypothesis: 1) If the disk is placed into each beaker with 100 units/ml of enzyme solution, then the time for the disk to float will be 30 seconds. 2) If the temperature of the solution is at 5 degrees Celsius,...

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enzyme lab

Lab 6.C Hypothesis: If enzyme activity is affected by the pH of a solution, then the enzymes will experience the greatest activity at a pH of 6. Variables: Independent Variables Dependent Variable Controls Four different pH values (10, 7, 6, and 3) Change in color of the solution The amount of potato extract, pH solution, and catechol used (1 cm +/- .1cm) Size of the test tubes Amount of time allowed for the catechol to sit with the potato extract and pH solution (20 minutes with...

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Determining the Properties of an Enzyme - Establish the Most Optimal Environment for a Peroxidase Enzyme

Description: A peroxidase enzyme, which was extracted from a brassica compestris (turnip), is tested under various conditions in temperature, pH level, and competitive inhibitor (hydroxylamine). ABSTRACT: In order to determine the properties of an enzyme, a peroxidase enzyme was extracted from a brassica compestris (turnip) and tested under various temperatures, pH levels, and by a competitive inhibitor (hydroxylamine). The enzyme activity was measured in various ways depending on the activity...

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