Zebrafish Research Paper

The pesticide had an adverse effect on the hatching success of eggs and survival rate of the embryo. The pesticide was assessed for its toxic potential and it was hypothesized that in the exposure water it will be harmful to the development of zebrafish embryos and our findings prove that a very low concentration in the water in the laboratory condition does have an impact on the development of the fish embryo. In the embryonic stage, the dead embryos significantly increased in response to the pesticide concentrations 0.0000134, 0.000134, 0.00134, 0.0134, 0.134, 1.34 and 13.4 µg/L and chorion of the egg provides no protection to the developing embryo (Kafeel Ahmad et al 2011). Early life stage is critical for the development of tissues and bones, and exposure to toxic
The result from the present study gives an idea of the type of effect the pesticide has on the embryo of zebrafish. Though the neurotoxicity of chlorpyrifos and cypermethrin has been much studied in rodents, little is known about the teratogenicity and developmental toxicity to fish in early life stages. In nature, fish are not exposed to single chemicals, but to a mixture of pollutants in aquatic system. The behavior of chemical mixtures in aquatic species is based on their toxic mode of action. Fish species possess specific characteristics for their use in environmental hazard and risk assessment (Jinyoung Lee and Jennifer, 2014). Significant differences in the spawning success have been reported after exposure to pesticides and effect on early life stages in zebra fish (Sisman, 2010). Fish embryo toxicity test is a non-animal test developed as an alternative for fish acute test, in Germany for the whole effluent toxicity testing of wastewater treatment by Adam et al (2011). Zebrafish and its