In pronounced dehydration, hypotension can occur. How would this affect the glomerular filtration rate of the kidney? What actions by the juxtaglomerular apparatus would occur to restore GFR?
The glomerular filtration rate would decrease with a decline in blood pressure. The juxtaglomerular apparatus participates in renal autoregulation and, when activated, increases GFR. The process involves the release of renin from the juxtaglomerular cells found in the afferent arteriole. Renin enters the bloodstream and converts inactive angiotensinogen to angiotensin I. Angiotension-converting