The following questions refer to Activity 1: Hematocrit Determination.
1. List the following values from Chart 1:
Hematocrit value for healthy male living at sea level in Boston = 48
Hematocrit value for healthy female living at sea level in Boston = 44
2. Were the values listed in question 1 within normal range?
3. Describe the difference between the male and the female hematocrit for an individual living in Boston. ERYTHROPOETIN SECRETION IN MALES STIMULATES THE PRODUCTION OF TESTOSTERONE. ERYTHROPOETIN MAKES RBC, AND RBC IS HIGHER IN MALES. SO MALES HAVE A HIGHER HEMATOCRIT
4. List the following values from Chart 1:
Hematocrit value for healthy male living in Denver = 55
Hematocrit value for healthy female living in Denver = 53
5. How did these values differ from the values for Boston?
THIS MALE AND FEMALE BOTH HAVE A HIGHER HEMOCRIT VALUE THAN THE MALE AND FEMALE IN BOSTON
6. Describe the effect of living at high elevations on a person’s hematocrit.
HIGHER ELEVATIONS HAVE LESS OXYGEN. SOMEONE LIVING IN HIGH ELEVATIONS NEED MORE RBC FOR OXYGEN.
7. Describe how the kidneys respond to a decrease in oxygen and what effect this has on hematocrit.
A DECREASE IN OXYGEN WOULD MAKE THE KIDNEYS PRODUCE MORE ERYTHROPOETIN TO STIMULATE RBC PRODUCTION
8. List the following values from Chart 1:
Hematocrit value for male with aplastic anemia = 32
& WBC for male with aplastic anemia = 1%
9. Were the values listed in question 8 within the normal range? Why or why not? 1-4 WAS NORMAL BECAUSE THEY ARE FROM HEALTHY INDIVIDUALS. #5 IS VERY LOW BECAUSE THE PERSON HAS APLASTIC ANEMIA AND THEIR BONE MARROW IS UNABLE TO MAKE ENOUGH RBC. #6 IS NOT NORMAL BECAUSE IT’S FROM AN ANEMIC PERSON AND THEIR BODY CAN’T PRODUCE ENOUGH HEMOGLOBIN.
10. List the following value from Chart 1:
Hematocrit for female with iron-deficiency anemia = 32
11. Was the value in question 10 normal or not? Explain.
NOT NORMAL BECAUSE IRON DEFIECIENCY CAUSES A DECREASE IN PRODUCTION OF HEMOGLOBIN WHICH RESULTS IN A LOWER HEMOCRIT.
Erythrocyte Sedimentation Rate
The following questions refer to Activity 2: Erythrocyte Sedimentation Rate.
12. Describe the effect that sickle cell anemia has on the sedimentation rate.
LOWER THAN NORMAL RATE
13. Why do you think that it has this effect? Hint: Sickle cell anemia alters the shape of red blood cells.
SICKLE CELL SHAPE ALTERS THE RBC AND DOESN’T ALLOW THEM TO SETTLE
14. Record the sedimentation rate for a menstruating female.
15. How did this value compare to the healthy individual? Why?
THIS VALUE IS HIGHER BECAUSE SHE HAS ANEMIA
16. What was the sedimentation rate for the iron-deficient individual?
17. What effect does iron deficiency have on ESR?
IRON DEFICIENCY CAUSES ELEVATED ESR
18. Record the following values from Chart 2:
ESR for person suffering from a myocardial infarction = 40
ESR for person suffering from angina pectoris = 5
19. Compare the values in question 18 and explain how they might be used to monitor heart conditions.
ESR CAN HELP DETERMINE HEART PROBLEMS SUCH AS MYOCARDIAL INFARCTION DUE TO INCREASED LEVELS AND ANGINA PECTORIS IF THE ESR WHITHIN NORMAL RANGE.
20. List some other conditions that ESR is used to monitor.
IRON DEFICIENCY, SICKLE CELL ANEMIA, CANCER, INFLAMMATORY DISEASES
The following questions refer to Activity 3: Hemoglobin (Hb) Determination.
21. Describe the ratio of packed cell volume to Hb (hemoglobin) obtained for the healthy male and female subjects.
3:1 IS THE RATIO OF PACKED CELL VOLUME TO GRAMS OF Hb
22. Describe the ratio of packed cell volume to Hb (hemoglobin) for the female with iron-deficiency anemia.
23. Is the female with iron-deficiency anemia deficient in hemoglobin?