Nucleic acids

Good Essays
Topics: Protein, RNA, Amino acid
Few recent advances have, for better or for worse, had such an impact on biological thinking as the discovery of base-pairing in nucleic acids. These complementariness principles do not only underlie current ideas on the structure of the nucleic acids, but they form the foundation of all speculations, more or less well- founded, on their physical properties (denaturation, hypochromic- ity, etc.), on the transfer of biological information from deoxy- ribonucleic acid to ribonucleic acid, and on the role of the latter in directing the synthesis of specific proteins. They form the basis of present explanations of the manner in which the amino acids are activated before being assembled to make a protein; they are being invoked incessantly in attempts to unravel the nucleotide code which is thought to be responsible for specifying the amino acid sequence of proteins.

It will, perhaps, surprise many readers, into whose ears a different version has been drummed for years, to learn that the first announcement of base-pairing in nucleic acids was made in an article, published early in 1950, which forms Chapter 1 of this book; the statement itself will be found on page 13. Those to whom it may sound unusually modest or restrained are asked to consider that at that time the new science of molecular biology did not yet exist.

should like to use this occasion to thank the several publishers for the permission to reprint these articles.

The last two chapters, Nos. 10 and 11, have not been pubHshed before and are of an entirely different kind, stepping forth, as they do, without the stately periwig of a list of references. They should be considered as a divertimento, though not without pas- sages in a minor key; specimens of a sort that rarely finds its way into a book dealing with scientific matters. Chapter 10 is a specimen of a recent lecture, as it was prepared for actual delivery, without undergoing the

You May Also Find These Documents Helpful

  • Good Essays

    nucleic acid

    • 1224 Words
    • 5 Pages

    UNIT 4. NUCLEIC ACIDS I.BASIC CONCEPTS II.CLASSES III.CHEMICAL NATURE IV.FUNCTION I.BASIC CONCEPTS NUCLEIC ACIDS polymeric macromolecules, or large biological molecules, essential for all known forms of life are made from monomers known as nucleotides Each nucleotide has three components: a 5-carbon sugar, a phosphate group, and a nitrogenous base If the sugar is deoxyribose, the polymer is DNA. If the sugar is ribose, the polymer is RNA. Together with proteins, nucleic acids are the…

    • 1224 Words
    • 5 Pages
    Good Essays
  • Better Essays

    Nucleic Acids

    • 1097 Words
    • 5 Pages

    Chapter 4: Nucleic Acids and the RNA World 1. 4.1 – What is a Nucleic Acid? * Nucleic acids are made up of monomers called nucleotides * Three components of a nucleotide: 1. Phosphate group—attached to the 5’ carbon 2. Sugar – carbonyl group and several hydroxyl groups 3. Nitrogenous base * The prime (‘) symbols indicate the carbon being is part of the sugar—not attached to the nitrogenous base. * Four different nucleotides, each of which contains a different nitrogenous…

    • 1097 Words
    • 5 Pages
    Better Essays
  • Good Essays

    Nucleic Acid

    • 1404 Words
    • 6 Pages

    Farrell cengage.com/chemistry/campbell Chapter Nine Nucleic Acids: How Structure Conveys Information Paul D. Adams • University of Arkansas Nucleic Acids • Nucleic acid: a biopolymer containing three types of monomer units • a base derived from purine or pyrimidine (nucleobases) • a monosaccharide, either D-ribose or 2-deoxy-D-ribose • phosphoric acid • RNA (Ribonucleic Acid) • DNA (Deoxyribonucleic Acid) Nucleic Acids • Levels of structure • 1°structure: the order of bases…

    • 1404 Words
    • 6 Pages
    Good Essays
  • Good Essays

    Nucleic Acids

    • 444 Words
    • 2 Pages

    one of two very similar pentose rings. Ribonucleic acids contain the sugar ribose. Deoxyribonucleic acids contain the sugar deoxyribose. The only difference between these two sugars is that deoxyribose contains one oxygen atom less than ribose. Pentose sugars are essential because they are involved in linking different nucleotides together by condensation reactions. The Nitrogen-Containing Bases There are two types of bases found in nucleic acids. The purine bases have two nitrogen containing rings…

    • 444 Words
    • 2 Pages
    Good Essays
  • Better Essays

    This paper is an analysis conducted on Nucleic Acids through a variety of tests specifically, Dische, Murexide, Wheeler-Johnson and Phosphate Tests in order to exemplify structural features of nucleic acids as well as identify the principle involved in each chemical test. Different procedures and different test compounds were applied, and results were noted as for changes in colors of precipitates or solutions. For Dische Test, light blue was obtained for RNA and dark violet for DNA. For Murexide…

    • 905 Words
    • 3 Pages
    Better Essays
  • Satisfactory Essays

    Quiz on Nucleic Acid

    • 574 Words
    • 3 Pages

    Assignment 2: Answer Sheet (LSM 1401 Semester 2 AY2011/12) Nucleic Acid Virtual Laboratories |Name | | |Matriculation number | | |A. DNA Extraction Virtual Lab [2 marks]…

    • 574 Words
    • 3 Pages
    Satisfactory Essays
  • Satisfactory Essays

    Nucleic Acids Study Guide

    • 302 Words
    • 2 Pages

    Nucleic Acids Study guide I. Basic Info A. The chemical link between generations, the source of genetic info chromosomes B. They duplicate amino acid sequences in proteins C. Serves as Blue print of life II. Make up A. They have three parts • 5 Carbon Sugars • Base • A phosphate group III. DNA (Deoxyribonucleic Acid) A. Has a double helix B. Composed of repeating Nucleotides connected together C. Guanine → Cytosine D. Thymine →Adenine E. Linked by hydrogen bonds F. Sugar…

    • 302 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    Nucleic Acid and Rna World

    • 1770 Words
    • 8 Pages

    Freem an, Biological Science, 4e, Chapter 4 Chapter 4 - Nucleic Acids and the RNA World Learning Objectives: Students should be able to... • Sketch a nucleotide, label its three basic parts, and identify the 2', 3', and 5' carbons. • Make another sketch showing the primary and secondary structures of DNA. • Describe the primary, secondary, tertiary, and quaternary structures of RNA, and explain in what ways RNA differs from DNA. • Explain why and how the secondary structure of DNA allows…

    • 1770 Words
    • 8 Pages
    Good Essays
  • Powerful Essays

    MODULE 2: GENETICS, VARIATION AND NATURAL SELECTION SPECIFIC OBJECTIVES & EXPLANATORY NOTES 1. Structure and Roles of Nucleic Acids 1.1 illustrate the structure of RNA and DNA using simple labelled diagrams; The genetic substance found in all organisms called DNA or deoxyribonucleic acid is a kind of nucleic acid. Nucleic acids consist of two long polymers of simpler units, called nucleotides; that are composed of three (3) main units as shown below: 1) A pentose sugar (deoxyribose…

    • 9497 Words
    • 38 Pages
    Powerful Essays
  • Good Essays

    ISOLATION AND CHARACTERIZATION OF NUCLEIC ACIDS Jan Eric C. Balete, Dorinne P. Barretto, Divine Trisha Angela T. Batac, Neill Steven C. Cachuela, Karel D. Cartagena Group 2 2C Medical Technology Biochemistry Laboratory ABSTRACT fgdfgdgdfgfdfgd INTRODUCTION Nucleic acids are informational molecules with their primary structure containing a code or set of directions by which they can duplicate themselves and guide the synthesis of proteins. [1] They are very large molecules built from subunits…

    • 604 Words
    • 2 Pages
    Good Essays