# KDIGO Clinical Law Case Study

Good Essays
1062 Words
Grammar
Plagiarism
Writing
Score
KDIGO Clinical Law Case Study
According to KDIGO Clinical Practice Guidelines, acute kidney injury is the condition that the kidney structure and function is being affected. These condition can refer to the acute kidney diseases and disorders. In AKI, there are three important factors that needed to be considered. For instances, the kidney function estimation, fluctuations in the creatinine production and fluid balance.
A study conducted by Jelliffe et al. (2002) found that in AKI, the function of the kidney is in non-steady state. Hence, the Jelliffe equation was created in order to estimate the glomerular filtration rate in this non-steady-state kidney function. In the year of 2002, Jelliffe has published an equation to estimate the unstable kidney function of the patients.
(2017), they found that these equations can be applied for the non-steady state serum creatinine which is in AKI patients. These equations can use to calculate the clearance in the AKI patients. Other than Modified Jelliffe’s equation and also Jelliffe’s equation, the Chiou and Brater equation can be applied in the AKI patients too. The differences between these equation is about the time. For the Jelliffe and Brater equations, foe the two serum creatinine values, they need at least 24 hours period in between them. For Chiou equation, the period of time is based on hour. The clearance can be estimated based on hourly for the AKI patients. The equation is shown in Figure 3 and …show more content…
This is due to this equation will overestimate the GFR if there is a high baseline of GFR. In this study, they found that if a patient have fluid accumulate in their body, then the Cockcroft-Gault will overestimate the GFR. In contrast, this Cockcroft–Gault equation is commonly used to measure the GFR in the CKD patients. So, it is applied on the CKD patients but not in AKI patients. Furthermore, BSA is not adjusted in this equation, thus, it will also lead to the overestimation of GFR in AKI patients when compared to the Jelliffe

## You May Also Find These Documents Helpful

• Good Essays

2. Explain why transferrin levels in the blood are not increased in ACD patients, unlike in IDA patients.…

• 855 Words
• 3 Pages
Good Essays
• Powerful Essays

-A low hemoglobin (8.5) and low hematocrit (25%) and low RBC’s may affect my patient by her exhibiting a faster than normal heartbeat, fatigue, feeling short of breath, lack of energy, and pale skin and gums.…

• 1606 Words
• 7 Pages
Powerful Essays
• Satisfactory Essays

Patients’ base line serum creatinine is 1.5 to 1.7, patients laboratory studies from this morning indicates a BUN of 101 and a creatinine of 3.9.…

• 599 Words
• 3 Pages
Satisfactory Essays
• Good Essays

These values are compared to accepted reference ranges to find abnormal values. According to JJ’s lab values, her RBC’s, Hgb and Hct are below the lower end of the reference ranges for all three values. These objective data provide evidence that JJ is anemic. To further classify the anemia and help determine the underlying cause, the MCV can be calculated by using the Hct and RBC values. It is determined that JJ’s MCV is 85 fL/cell, which is within the reference range of normocytic anemia (81-99 fL/cell). As mentioned above, one of the causes of normocytic anemia is acute blood loss. Since her PMH does not mention chronic disease or any other condition that would result in blood loss, the evidence suggests that JJ’s anemic condition is possibly due to acute blood loss during her…

• 393 Words
• 2 Pages
Good Essays
• Satisfactory Essays

8. The mean severity for renal disease for the research subjects was a score of 6.74 as shown by the relevant study results. The information also says the SD is 2.97, which tells the dispersion of the renal disease severity scores. There is no significant difference in severity scores between the control and experimental groups. It is important that the patient’s show a…

• 464 Words
• 2 Pages
Satisfactory Essays
• Satisfactory Essays

Chawla, L., Eggers, P., Star, R. and Kimmel, P. (2014). Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes. New England Journal of Medicine, 371(1), pp.58-66.…

• 343 Words
• 2 Pages
Satisfactory Essays
• Good Essays

b- All of the plasma proteins are too large to fit through the filtration slits…

• 846 Words
• 4 Pages
Good Essays
• Good Essays

To find research on this kidney condition, I accessed the Galileo database. I searched for…

• 1414 Words
• 6 Pages
Good Essays
• Satisfactory Essays

Mrs. Jones’ kidneys are impaired. The kidneys regulate their own blood flow as well as GFR. When the kidneys become hypoperfused in Mrs. Jones case, narrowing of the renal arteries, and vessels in the kidneys dilate with the help of prostoglandims to facilitate the flow.…

• 391 Words
• 2 Pages
Satisfactory Essays
• Powerful Essays

Illness is ‘a state of poor health’.’If a person has an illness they can experience a range of different symptoms, and tests may not always identify the cause as it could be just a cold or a cough. Illnesses identify a condition that exists which causes someone harm or pain. Also being ill usually requires the patient’s condition to be classified according to the medical knowledge and practise. If you’ve an illness then symptoms like coughs, sore throats, runny nose etc are all examples. Illnesses are usually just short term and last days maybe even a week or so. Illness also looks at the biomedical model of health as it focuses on the NHS and doctors/hospitals etc. It highlights the expertise of the medical profession.…

• 1897 Words
• 8 Pages
Powerful Essays
• Best Essays

Drueke TB, Locatelli F, Clyne N, Eckardt KU, Macdougall IC, Tsakiris D, et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med. 2006 Nov 16;355(20):2071-84.…

• 1021 Words
• 5 Pages
Best Essays
• Better Essays

The body needs to maintain equilibrium to function properly in everyday life. The most important substance it must regulate is water; water is everywhere in our body and its balance is essential for proper body function.…

• 1290 Words
• 10 Pages
Better Essays
• Good Essays

The medicinal records that Keira conveys to this arrangement demonstrate that her hemoglobin A1c has never been t know about the need to keep her pulse somewhat less than 130/80 mmHg for both cardiovascular and renal health.11…

• 445 Words
• 2 Pages
Good Essays
• Powerful Essays

All patients were radiologically analyzed by CT to identify renal stone density. CR is used to measure the size of stones in the same patients.…

• 2939 Words
• 12 Pages
Powerful Essays
• Good Essays

Particularly, the PK parameters of ICU patients were recorded. At steady state, the AUC of the three multiple dosage regimens (70/35 mg, 70 mg q.d, 100 mg q.d) of caspofungin in ICU patients were 74.5 mg·h/L, 155.5 mg·h/L, 218.4 mg·h/L, respectively. The Cmax were 6.5 mg/L, 11.5 mg/L, 16.9 mg/L, respectively. After simulation of the reduction dose of 50/25 mg and dose escalating of 70 mg q.d, 100 mg q.d of moderate HI patients, we got the PK parameters of these patients. The AUC of these patients were 92.6 mg·h/L, 178.6 mg·h/L, 280 mg·h/L, respectively. The Cmax were 5.8 mg/L, 10.9 mg/L and 15.3mg/L, respectively. The results of all patients are shown in Table 3.…

• 764 Words
• 4 Pages
Good Essays