Preview

Hepatopulmonary Syndrome Research Paper

Better Essays
Open Document
Open Document
796 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Hepatopulmonary Syndrome Research Paper
The liver is a vital organ within the human body. The normal pathophysiology of the liver is to perform critical functions which rid the body of harmful toxins and substances. The liver rids the body of its harmful toxins by the way it secretes chemicals and produces bile. Bile is a substance that helps the breakdown of lipids and salts so that they are easily absorbed into the intestine to be secreted out of the body.
Vasodilators are medications which cause the blood vessels within the human body to dilate. Vasodilators just don't affect the vessels, but also the muscles and the walls of veins and arteries within the human body. Vasodilators are used to prevent the muscles in the body from tightening which allows easy blood flow throughout
…show more content…
An increase in the heart rate and cardiac output occurs which dilates the blood vessels causing the blood to flow throughout the liver more efficiently. (Schwartz JS, 1987)
Hepatopulmonary syndrome (HPS) is caused by liver disease, HPS occurs from the vasodilation of the blood vessels. When vasodilation occurs it causes a shortness of breath due to the exertion and loss of energy, and it also causes hypoxaemia which is due to vasodilation. (Spagnolo, Zeuzem, Richeldi, & Bois, 2010) In saying this pulmonary vasodilation occurs during liver failure due to being mediated by many different endogenous vasoactive molecules such
…show more content…
Q or perfusion is the blood flow of deoxygenated blood from the heart. This blood flows through the pulmonary arteries and into the capillary beds. This is where oxygen and nutrient exchanges take place
With that explained it tells us that alveoli are the smallest airways and that capillaries are the smallest blood vessels within the human body. They also both are only one cell thick. Within Ventilation/perfusion mismatch, the oxygen from the alveoli transfers to the capillaries and then the carbon dioxide from the capillaries transfers to the alveoli and this is what is measured. The amount of air the reaches the alveoli which are then divided by the amount of blood which flows through the capillaries.
So now we can understand that V/Q mismatch is the areas within the lungs where the alveoli's and capillaries do not line up which is also called the dead space. This just shows that the lungs aren't the same throughout. Some parts of the lungs are more perfused where others are more ventilated.
The equation for Ventilation/perfusion mismatch

You May Also Find These Documents Helpful

  • Good Essays

    Case Study 3

    • 322 Words
    • 2 Pages

    a. The primary cause of the patient’s respiratory distress comes from hypoxemia. The hypoxemia is caused by heart failure possibly from emboli and obstructions in the circulatory system, which is causing the patient to breathe harder and faster to compensate. The mild respiratory alkalosis/hypoventilation is from the hypoxemia. The emboli is causing VA/Q mismatch.…

    • 322 Words
    • 2 Pages
    Good Essays
  • Better Essays

    Alcohol Crihhosis

    • 1844 Words
    • 8 Pages

    Alcoholic cirrhosis is charactered by the replacement of the destroyed liver cells with the scar tissue (Farrell & Dempsey, 2009, p.1167). The increased liver scar tissue result in the failure of liver function to synthesis protein, clotting factors, the substances and manifestation of portal hypertension (Farrell & Dempsey, 2009, p.1168). In liver cirrhosis, the live tend to be large and its cells loaded with fat, that it causes the liver become firm and sharp edge noticeable on palpation (Farrell & Dempsey, 2009, p.1168). Moreover, as the rapid enlargement of the liver, the tension on the fibrous covering of the live is produced and may causes the abdominal pain (Farrell & Dempsey, 2009, p.1167). The late manifestation are due partly to chronic failure of liver function is the obstruction of the portal circulation as the blood cannot passage through the liver and back up into the spleen and Gastrointestinal (GI) tract (Farrell & Dempsey, 2009, p.1168). Therefore, the GI tract cannot function properly which result into the decreasing ability of indigestion and altered bowel function (Farrell & Dempsey, 2009, p.1168). Fluid rich in protein may be moved from the vascular system to the peritoneal cavity and…

    • 1844 Words
    • 8 Pages
    Better Essays
  • Good Essays

    The high pressure then puts more pressure on the right ventricle of the heart, causing it to get bigger. This then causes the right ventricle gradually becomes weaker and loses its ability to pump enough blood to the lungs stronger than usual.…

    • 3143 Words
    • 13 Pages
    Good Essays
  • Powerful Essays

    Module 1 Pre Assessment

    • 1934 Words
    • 11 Pages

    CORRECT ANSWER A) Pulmonary congestion YOUR ANSWER A) Pulmonary congestion Deoxygenated blood from the right ventricle flows through the right and left pulmonary arteries…

    • 1934 Words
    • 11 Pages
    Powerful Essays
  • Better Essays

    The cardiovascular system The heart is a major organ in the body, this organ pumps blood around the body, through veins, capillaries and arteries. The blood carries oxygen to our cells and also carries waste products which include water and carbon dioxide, which are products of respiration. Blood also helps spread out salts, enzymes, urea, nutrients, hormones and heat across the body.…

    • 2117 Words
    • 7 Pages
    Better Essays
  • Good Essays

    Unit 7 Lab Report

    • 680 Words
    • 3 Pages

    6-5: Is the FEV1 reduced or increased? 6-6: Which of these two changed more? 6-7: Explain the physiological reasons for the lung volumes and capacities that changed in the spirogram for this…

    • 680 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Acidosis and Alkalosis

    • 772 Words
    • 4 Pages

    * Respiratory acidosis results from a build-up of carbon dioxide in the blood (hypercapnia) due to hypoventilation. It is most often caused by pulmonary problems, although head injuries, drugs (especially anaesthetics and sedatives), and brain tumors can cause this acidemia. Pneumothorax, emphysema, chronic bronchitis, asthma, severe pneumonia, and aspiration are among the most frequent causes. It can also occur as a compensatory response to chronicmetabolic alkalosis.…

    • 772 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Blood Flow to the Liver

    • 287 Words
    • 2 Pages

    Functions of the liver: produce bile, detoxify the blood, storage for nutrients, synthesize plasma proteins and break down RBC’s…

    • 287 Words
    • 2 Pages
    Good Essays
  • Good Essays

    spirometry report

    • 952 Words
    • 4 Pages

    1. What is the residual volume and why is it important to normal respiratory function?…

    • 952 Words
    • 4 Pages
    Good Essays
  • Good Essays

    super-size me analysis

    • 513 Words
    • 3 Pages

    When the liver gets fat, your cholesterol level increases. Cholesterol is the fat content in your blood, when you have a high cholesterol the blood vessels narrow. As a result your blood pressure increases as well, and the chance of getting a hart desease increases.…

    • 513 Words
    • 3 Pages
    Good Essays
  • Good Essays

    pulmonary stenosis, which reduces blood flow to the lungs as well as tetralogy of fallots,…

    • 1196 Words
    • 5 Pages
    Good Essays
  • Good Essays

    Hypovolemic Shock Case

    • 563 Words
    • 3 Pages

    2. Explain the perfusion triangle as it relates to three components of circulation The perfusion triangle consists of the heart (pump), blood vessels (pipe), and blood (fluid). When everything in the perfusion triangle is working properly, adequate blood and oxygen are provided to all cells in the body. When there is pump failure, pipe failure, or fluid loss, circulation failure occurs and there is not enough oxygenated blood to be supplied through the body.…

    • 563 Words
    • 3 Pages
    Good Essays
  • Good Essays

    In the early stages of hepatic disease, systemic and renal hemodynamic variations are found while kidney function tests are normal. The dynamic monitoring of haemodynamic changes in the kidney are important for determining renal blood flow and predicting the development of HRS in patients with chronic liver disease and portal hypertension (Wang et al., 2011).…

    • 712 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    Pulmonary Embolism Essay

    • 2665 Words
    • 11 Pages

    The obstruction of pulmonary artery, which can be acute or chronic, is caused by three major factors such as local trauma to the vessel wall, hypercoagulability, and stasis of blood, which is commonly called as Virchow’s triad( Jarreau et al,2008) . Acute symptoms can be differentiate from chronic depending upon the onset of symptoms . For acute PE, the onset of symptoms is sudden whereas chronic PE symptoms can take place over a period of time ( Thompson and Hales,2012). Almost 75% of patients who develop PE have experienced DVT as mostly the thrombus arises from the lower limbs.( Kearon,2003).…

    • 2665 Words
    • 11 Pages
    Powerful Essays
  • Good Essays

    The second largest organ in the human body is the liver, weighing roughly three pounds.1 The liver is located on the upper right side of the abdomen beneath the rib cage.1, 2 It performs numerous functions in the body including energy metabolism, processing of foods into nutrients used for body processes, and removal of toxic substances from the blood system.1, 2 A variety of factors can affect the liver; for example, genetic disorders, hepatitis viruses, alcohol abuse, obesity, and diabetes.2 Damage to the liver may result in scarring or cirrhosis over time, which could lead to liver failure and an increase risk of mortality.2 Signs and symptoms of liver disease may include jaundice (yellowing of skin and eyes), abdominal pain and swelling,…

    • 1378 Words
    • 6 Pages
    Good Essays