Lab 1: Synthesis of Aspirin Introduction: The purpose of this lab was to demonstrate the ability to easily alter the molecular structure of a compound to greatly increase its utility. In this case‚ an acetyl group was added to salicylic acid‚ a naturally occurring compound with significant pharmaceutical value. Without the addition of the acetyl group‚ salicylic acid is an irritant to the gastro-intestinal (GI) tract. Once the acetyl group is added via a simple reaction‚ acetylsalicylic
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Zinc acetate dehydrate was dissolved in a mixture of absolute ethanol and monoethanolamine (MEA) yielding to a precursor concentration of 0.4 M .The MEA to zinc acetate molar ratio was set to 1. For doped films‚ cerium nitrate was added to the mixture with an atomic percentage fixed at 0.1‚ 0.3‚ 0.5‚ 0.7‚ and 0.9 at.% Ce‚ respectively. The resulting sols were magnetically stirred at 60°C for 1 hour and then aged at room temperature for one week to get clear and transparent homogeneous solutions. Prior
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INTRODUCTION Isopentyl acetate‚ "banana oil"‚ is a naturally occurring compound that possesses a distinctive odor. It is found in bananas‚ as well as many other organisms. This experiment attempts to produce isopentyl acetate by heating under reflux‚ which involves heating the mixture in a flask with a condenser placed vertically in the neck since any escaping vapours condense and run back into the flask‚ by combining isopentyl alcohol with acetic acid and an acid catalyst. The product was isolated
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Ethyl Acetate – NaOH Reaction Kinetics Experiment Martin Novick Group 14‚ Chemical Engineering Laboratory Submitted to Prof. David B. Henthorn September 25‚ 2012 Summary The goal of this project was to determine the pre-exponential factor‚ k o ‚ the activation energy‚ E‚ and the reaction rate constants‚ k‚ of the saponification process of ethyl acetate using sodium hydroxide (NaOH) at 5 temperature between 15 and 25 degrees Celsius. Two trails were performed at temperatures 16‚ 18‚ 20‚ 22‚ and 24
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Synthesis of Aspirin Learning Goals 1. To synthesize aspirin from salicylic acid and acetic anhydride. 2. To purify the crude product by Recrystallization. Introduction Most drugs are chemical compounds which are described as "organic compounds" because they are comprised primarily of the elements carbon‚ hydrogen and oxygen. The present experiment will be the synthesis of a familiar organic compound called aspirin. The common chemical name is acetylsalicylic acid. Aspirin‚ the
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Jeana Greaves Chem3301-112 June 19‚ 2013 Synthesis of Aspirin from Methyl Salicylate Introduction The synthesis of Aspirin (Acetyl Salicyclic Acid) began with methyl salicylate and sodium hydroxide as the reagent. The polar oxygen accepts the electrons from now positively charged hydrogen. The positively charged sodium disassociates leaving the hydroxide ion with a negative Scheme 1 shows the mechanisms that were demonstrated during the synthesis of Aspirin. charge that attracts to the positively
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The purpose of this experiment is to synthesize isopentyl ester by an esterification reaction between a carboxylic acid and an ester. Carboxylic esters‚ like isopentyl acetate‚ are normally used to create artificial flavors. In the preparation of isopentyl acetate‚ esterification of acetic acid and isopentyl alcohol occurs. Esterification is an equilibrium shift to the product side using an excess of one of the starting components. In this experiment‚ the excess reagent is acetic acid because it
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Purpose Acetophenetidin can be formed through two methods‚ Williamson ether synthesis and amide synthesis. By working in groups of two we were able to complete both methods of synthesis routes. The end result should be the synthesis of a similar product‚ by verification between the two individuals. Reaction Experiment and Observations Amide Synthesis of Acetophenetidin The Synthesis reaction began by removing the colored impurities from the p-phenetidine‚ accomplished by mixing
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1.TITLE: To prepare isopentyl acetate (isoamyl acetate) 2. AIM: To make an ester referred to as banana oil from acetic acid and isopentyl alcohol 3.THEORY: This ester is often referred to as banana oil‚ since it has the familiar odor of this fruit O O CH3 H+ CH3 CH3C OH +
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Synthesis of Acetaminophen Lab Report Bijal Patel‚ 20467049 Partner: Poojan Parikh T.A.’s: Long Pu CHEM 123L‚ Section: 006‚ Rm: ESC 149 Tuesday February 4‚ 2013‚ 2:30pm-5:20pm Experiment Done: Tuesday January 22‚ 2013 Introduction Acetaminophen was first introduced in 1955 (Richman‚ 2004). It is an over-the-counter drug that relieves pain and reduced fevers. Acetaminophen is considered an alternate to aspirin since it does not irritate the stomach (Richman‚ 2004). It also has very
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