Cause of Cystic Fibrosis Cystic Fibrosis is caused by a mutation in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. The CFTR gene codes for the CFTR protein which is a chloride ion channel belonging to the ABC (what does it stand for) transporter superfamily of proteins. The CFTR proteins are normally located on the apical plasma membrane of epithelial cells in the airways‚ lungs‚ skin‚ digestive organs (E.g. - the pancreas and intestine) and reproductive tracts (E.g. - sperm
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Cystic fibrosis is a disease passed down through families‚ a genetic disorder‚ that causes thick‚ sticky mucus to build up in the lungs‚ digestive tract‚ and other areas of the body. Cystic fibrosis is where it affects the cells that produce mucus‚sweat and digestive juices. These fluids are normally thin and slippery‚ but in Cystic fibrosis‚ a defective gene causes the fluids to become thick and sticky plugging up tubes‚ ducts and passageways in the human body especially in the lungs and pancreas
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Krickett Davis Zachary Mock Cystic Fibrosis Case Study: Part I Questions: The Meeting Consult your textbook and trustworthy Internet sites to answer the following questions: 1. Which organs are affected by cystic fibrosis? What are the disease symptoms? Organs that are affected by cystic fibrosis include the lungs‚ pancreas‚ liver‚ sweat glands‚ reproductive organs‚ nose and sinuses. The symptoms of cystic fibrosis include coughing with mucus coming up‚ wheezing‚ breathlessness‚ decrease in ability
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On researching new developments in the treatment of cystic fibrosis‚ I came across a very interesting article: “Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect.” In the article‚ Viet et al1 reveal the potential application of the silencing of RPL12 (Ribosomal Protein L12)‚ to correct the ΔF508-CFTR biogenesis defect. As you know‚ cystic fibrosis is caused by a defect in the CF transmembrane conductance regulator (CFTR gene)‚ or more specifically‚ mutations
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to define the term primary health and explain its origins and development; also touching on the impact of primary health on the nursing profession. It will commence with an introduction to primary health and primary health care. Covered in this paper will also be the influence that primary health care has had on nursing and any alterations associated with its implementation. Primary health care aims to provide a health care framework that steps away from the acute care focus and brings to the forefront
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The Cystic Fibrosis Foundation describes Cystic Fibrosis as “a progressive‚ genetic disease that causes persistent lung infections and limits the ability to breathe over time” (www.cff.org). People with Cystic Fibrosis suffer from an increase of mucus buildup in the lungs‚ pancreas‚ and the liver; Cystic Fibrosis also affects the Nose and sinuses‚ as well as the sweat glands. The only way that CF is transmitted is by a Cystic Fibrosis positive carrier. When two positive carriers have a baby there
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in her family history is a great-aunt who died of respiratory disease at 20 years old. Test results have shown high levels of sodium and chloride in her sweat. Patient A has Cystic Fibrosis‚ which is shown by her respiratory and digestive system symptoms. Cystic Fibrosis is a genetic mutation that mutates the cystic fibrosis transmembrane conductance regulator protein(CFTR). When CFTR is working properly‚ it allows chloride to leave the cell and create a balance between the amount of chloride and
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were once an imminent death sentence have made outstanding medical advances. Cystic fibrosis (CF) is a genetic disorder that decreases the effectiveness of the lungs due to a mucous buildup. In the late twentieth century patients with CF could only to expect to live a few years but since 2006‚ life expectancy has risen to 36 years of age.1‚2 Cystic fibrosis is a genetic disorder that causes a mutation of the cystic fibrosis transmembrane conductance regulator (CFTR). The most common mutation is a deletion
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Impact of Institute of Medicine on Nursing Ermina Rosic Grand Canyon University: NRS-430V December 14‚ 2014 The Institute of Medicine Report On Future of Nursing The Institute of Medicine (IOM) is a national‚ independent‚ non-profit organization whose purpose is to provide guidance‚ advice‚ and analysis of the field of medicine. The recent IOM report regarding the future of nursing gives us a glimpse of the dynamic and progressive changes that the field of nursing will experience in the coming
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FOCUS: “Treatments for lung conditions Cystic Fibrosis sufferers contend with” Word Count: 1461 This essay will aim to explore the different ideas and concepts of using several types of medication for cystic fibrosis sufferers. Cystic fibrosis is a genetic disorder that affects thousands of children and adults across the United Kingdom; it mainly affects Caucasian beings and is a well-known disease throughout the world‚ but has no cure only treatments to ensure a better quality of life
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