Nerve Impulses: Activity 2: Receptor Potential Lab Report Pre-lab Quiz Results You scored 100% by answering 4 out of 4 questions correctly. 1. Assuming that the resting potential of a sensory neuron is -70 mV‚ which of the following represents a depolarization? You correctly answered: c. a change to -60 mV 2. Which of the following is a sensory modality (type of sense)? You correctly answered: e. all of the above 3. Which of the following is a sensory stimulus? You correctly answered: d.
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Cutaneous receptors are sensory receptors located in the dermis‚ which is a layer of the skin. These receptors are responsible for sensations of touch‚ pressure‚ heat‚ cold‚ and pain. They are classified asmechanoreceptors which are associated with pressure‚ thermoreceptors which are associated with temperature‚ and nociceptors which are associated with pain (Brodal). Functional Anatomy There are five mechanoreceptors‚ free nerve endings‚ Meissner’s corpuscles‚ Pacinian Corpuscles‚ Merkel’s
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concluded my discovery of space worm touch receptors is definite. Regardless of the type‚ sensory receptors are influenced by physical actions and various stimulus. My research and experiments show that space worm touch receptors are no different. Stimulus is a change discernible by the body (Sherwood 2004) or in my case‚ a space worm. Certain receptors like touch receptors respond to stimulus weakly or strongly when involved with a different stimulus (Sherwood 2004). This perfectly related to
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have evolved to block motor activity of their prey by releasing toxins. Some others from coral and plants use different blockage that is induced by cholinergic agents for protect themselves from predation. The high affinity and selectivity of these toxins enabled the type of ACh receptors to emerge as the first chemically characterized neurotransmitter receptor. 2. SYNTHESIS‚ STORAGE AND RELEASE OF ACETYLCHOLINE The biosynthesis and storage of ACh can be divided into three processes that
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PHYSIOLOGY Transmembrane receptors composed of excitable G-proteins‚ which cross the cell membrane and link selectively with extra cellular ligands are called adrenoceptors. They are also termed as α-2 Adrenoceptor agonists α-2 adrenergic receptors. Three α-2 isoreceptors - α-2a‚ α-2b and α-2c of adreno receptor bind α-2 agonists and antagonists with similar rapport and share an amino acid composition homology of roughly 70 to 75%. The efficacy of sub receptor specific agonists that constrains deleterious
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Receptor Protein Protein that binds to a specific single molecule‚ enabling the cell to respond to the signal molecule. i.e. The muscles of a person exercising can not contract without receptor proteins and signal molecules that tell the muscles when to contract and when to relax. Second Messenger Signal molecule produced in response to the binding of a chemical signal. Acts as a signal molecule in the cytoplasm. Signal Molecule Carries information throughout the body and to other
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in the visceral region. An example is Irritable Bowel Syndrome (IBS) which has chronic pain as a symptom. A receptor that has been seen to be present and upregulated in this disease are Transient Receptor Potential (TRP) channels‚ and in particular‚ Transient Receptor Potential Vanilloid type 1 (TRPV1) and Transient Receptor Potential Ankyrin Type 1 (TRPA1)(15‚18). In this review‚ TRPV1 and other channels‚ such as TRPA1 induced pain are looked at. As possible drug targets‚ there have been studies
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metabolized or excreted ELIMINATION Drug at site of action Pharmacologic effect Pharmacodynamics Toxicity Efficacy PHARMACOLOGY Pharmacodynamics Actions of drug on the body Specific to a drug/ class of drugs • Interaction with target sites (receptors/enzymes) • Effects at site of action • Dose-response relationship • Reduction in symptoms • Modification of disease process • Unwanted/side effects • Drug interactions • Inter- and intra-patient differences Pharmacokinetics Actions of body on
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Adrenergic medications affect the four receptors‚ a1‚ a2‚ B1 and B2. The sympathetic nervous system triggers the secretion of epinephrine and norepinephrine. Epinephrine is a hormone and norepinephrine functions as a hormone and neurotransmitter. First we will take a look at the Alpha 1 receptors. These Alpha 1 receptors cause vasoconstriction of vascular smooth muscles. They are located on the post synaptic membranes of effector organs‚ such as on gastral and urinary sphincters. Some are located
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How do skin receptors’ distribution change one’s reaction to pain in different areas of your body? Aim: Our senses are responsible for receiving information in the outside environment and sending it to our central nervous system‚ where this information is then interpreted. Organs such as the skin‚ known as sense organs‚ have specific neurons named receptors‚ which are each responsible for responding to specific types of stimulus. The receptors responsible for identifying our sense of touch are distributed
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