The genetic disorder which I have chosen as the subject of my report is hemophilia. There are two types of hemophilia‚ hemophilia-A and hemophilia-B. The clinical symptoms of both are very similar so for the purposes of this paper I have chosen to concentrate on hemophilia-A. Hemophilia-A is an X linked bleeding disorder resulting from a defect in a protein known as coagulation factor VIII. Since the disorder is X linked it is expressed mainly in males‚ who must have mothers who are carriers. Females
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Hemophilia A is a rare genetic disease that is characterized as a bleeding disorder. The disease‚ which presents itself in three different forms‚ mild‚ moderate‚ and severe‚ is dependent upon the production of the glycoprotein‚ coagulation factor viii. Although Hemophilia A produces a wide variety of serious symptoms‚ it is not necessarily fatal‚ and it is a direct result of a mutation that occurs on the gene F8 (4). Hemophilia A can be distinguished into three forms: mild‚ moderate‚ and severe.
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Background -Hemophilia A is an inherited disorder in which one of the proteins needed to form blood clots is missing or reduced. This lacking protein is known as blood clotting factor 8. Without F8‚ the blood cannot clot properly to stop bleeding and can result in excessive bleeding or disabilities. Hemophilia A -When blood is not able to clot and allow wounds to heal‚ this is a result of Hemophilia A Symptoms Include: -Prolonged bleeding from cuts -Excessive nose bleeds -Many large
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Anatomy and Physiology 1. Bone – Bones are made up of different types of tissues and join together to form the skeleton of the body. Their primary purpose is to provide structure for the body and to protect organs. It also serves as a storage site for minerals as well as producing and storing blood cells. The three different tissues that bones are composed of are: a. Compact Tissue – The dense outer tissue in a bone. b. Cancellous Tissue – The sponge like tissue inside the
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Hemophilia‚ Pediatric Hemophilia is a bleeding disorder that prevents a person’s blood from clotting properly. This means that it is harder for the person’s body to stop bleeding. Hemophilia is a lifelong condition that usually starts in childhood. A child with hemophilia may have prolonged bleeding after an injury or even without an injury. This occurs because the child has low levels of a type of protein that helps the blood to form clots. These proteins are called clotting factors. There are
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Patients and their families should be provided with psychological and social support. Hemophilia will lead the patient and family into financial burden and restrict them from normal living. The social worker and/or comprehensive care team members should provide information about the physical‚ psychological‚ emotional‚ and economic dimensions of hemophilia‚ in a way they can understand. They must be open and honest about all aspects of care‚ allow the patient/parents to work through their emotions
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Biology February 13th 2015 Hemophilia The genetic disorder I am discussing is Hemophilia‚ which is a rare disorder where a persons blood doesn ’t clot normally because it lacks sufficient bloodclotting proteins. If a person has hemophilia‚ they may bleed for a longer period of time after an injury because their blood does not clot normally. Hemophilia occurs when a person has a mutation in one of the clotting factor genes. 90% of people who have hemophilia have a mutation in the Factor VIII(8) gene
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symptoms The extent of bleeding depends on how severe the hemophilia is. In mild hemophilia‚ patients usually only have bleeding problems after tooth extraction‚ surgery or a bad injury or accident or might never have a bleeding problem. While in moderate hemophilia‚ they May have bleeding problems after minor injuries‚ such as sporting injuries and rarely have a bleed for no obvious reason. However in severe hemophilia‚ they often have bleeds into joints muscles and soft tissues • Can have bleeds
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Hemophilia is a genetic bleeding disorder. People who have hemophilia have a deficiency or an absence of a coagulation protein. A blood clotting factor is deficient or absent. Bleeding is most often into joints‚ such as the knee‚ elbow‚ or ankle‚ but bleeding can occur anywhere in the body. People with hemophilia bleed longer‚ not faster. The severity of hemophilia varies greatly. Hemophilia A and Hemophilia B are the most common genetic bleeding disorders. Hemophilia A is observed in 80 percent
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Introduction Hemophilia is a rare genetic blood clotting disorder that primarily affects males. People living with hemophilia do not have enough of‚ or are missing‚ one of the blood clotting proteins naturally found in blood. Two of the most common forms of hemophilia are A and B. In persons with hemophilia A (also called classic hemophilia)‚ clotting factor VIII is not present in sufficient amounts or is absent. In persons with hemophilia B (also called Christmas disease)‚ clotting factor
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