ALLEFRIN Chlorpheniramin maleate Properties: Allefrin (Chlorpheniramine maleate) has a very good therapeutic efficacy as histamine antagonizing agent with a very low incidence of side effects. It is one of the best effective antihistamines‚ although administered in a very low dosage which is far below any that are toxic. Its medical actions are due to the following pharmacological properties: a. It antagonizes the action of histamine on the plain muscles of the bronchioles‚
Free Asthma Allergy
invention of hairspray. Industrial suppliers can increase their net profit of aerosol hairspray production by analyzing and possibly optimizing their manufacturing process‚ mores specifically‚ the production of the most widely used aerosol propellant‚ dimethyl ether (DME). The optimization of a thermally coupled DME reactor (OTCDR) proves to be economical‚ energy sufficient‚ and increase the net profit of the industrial plant. It is in the best interest of industrial aerosol hairspray manufacturers to
Premium Methanol
Experiment #9 Isolation and Isomerization of Lycopene from Tomato Paste Goal / Purpose To extract the carotenoid pigments from canned tomato paste and separate them by column chromatography to obtain a solution that contains lycopene. Then record the ultraviolet-visible spectrum of this solution and analyze it for evidence of isomerization. Calculation List of Materials 4.0g tomato paste screw cap vial Chromatography column 25ml buret 50ml flask ring stamd and clamp 50% mixture
Premium Lycopene Chromatography Solvent
Lab Protocol #8 - Dehydration of 3‚3-dimethyl-2-butanol KEYWORDS: alkenes‚ E2‚ E1‚ carbocation stability‚ elimination A. Introduction. The dehydration of alcohols is an ELIMINATION reaction that is commonly used to form alkene molecules. The mechanism for the dehydration of alcohols consists of transforming the –OH functional group into a better leaving group by using a strong acid to protonate the alcohol. After –OH has been transformed into –OH2+‚ it becomes easier to break the σ-bond between the
Premium Distillation Organic reaction Alcohol
Available online at www.pharmacie-globale.info ISSN 0976-8157 Research Article PHARMACIE GLOBALE INTERNATIONAL JOURNAL OF COMPREHENSIVE PHARMACY DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR THE DETERMINATION OF CHLORPHENIRAMINE MALEATE AND PHENYLEPHRINE IN PHARMACEUTICAL DOSAGE FORM Mukesh Maithani*‚ Richa Raturi‚ Vertika Gautam‚ Dharmendra Kumar‚ Amrendra Kumar Chaudhary‚ Anand Gaurav and Ranjit Singh School of Pharmaceutical Sciences‚ Shobhit University‚ NH-58‚ Modipuram‚
Premium Analytical chemistry High performance liquid chromatography Chromatography
pharmacologically in active status. Inactive substance which has a metabolite that is active is referred to as a prodrug. Drugs are metabolized by the following processes; reduction‚ oxidation‚ conjugation‚ hydration‚ hydrolysis‚ condensation and isomerization. All these processes make the excretion of drugs easier from the body like that of a human being. For metabolism to occur‚ enzymes must be present. Enzymes are present in body tissues but they are concentrated in the liver. Rates
Premium Metabolism Carbon Carbon dioxide
1.0 INTRODUCTION 1.1 Occupational Safety and Health Administration& Process Safety Management The Occupational Safety and Health Administration (OSHA) is an agency to assure safe and healthful working conditions for working men and women by setting and enforcing standards and by providing training‚ outreach‚ education and assistance.The Occupational Safety and Health Act allows OSHA to issue workplace health and safety regulations. These regulations include limits on chemical exposure‚ employee
Premium Safety engineering Valve Fluid dynamics
Ashley Droddy CHM 235LL-Monday‚ 3/19/2012 & 3/26/2012 Part A: Dehydration of 1-butanol & 2-Butanol/Part B: Dehydrobromination of 1-Bromobutane & 2-Bromobutane Abstract The objective of this experiment is to successfully perform a dehydration of 1-butanol and 2-butanol‚ also dehydrobromination of 1-bromobutane and 2-bromobutane to form the alkene products 1-butene‚ trans-2-butene‚ and cis-2-butene. The dehydration reactions react under and acid-catalysis which follows an E1 mechanism
Premium Acid Organic reaction Alkene
Photochemical Synthesis of Benzopinacol and its Acid-Catalyzed Rerrangement Product Benzopinacolone M.E.G. Balita Institute of Chemistry‚ University of Philippines‚ Diliman‚ Quezon City Date Performed: February 18‚ 2011 Date Submitted: March 4‚ 2011 Abstract In this experiment it is aimed to synthesize benzopinacol through photochemical reaction of benzophenone and‚ benzopinacolone via acid-catalyzed rearrangement of benzopinacol. In this experiment‚ mixture of benzophenone‚ isopropyl
Premium Chemistry Ethanol
already raised concern that the maleate salt of Amlodipine‚ unlike the besylate and mesylate salts‚ suffer from intrinsic chemical instability resulting in the formation of a biologically active degradation product [17]. Some studies‚ including that by Suh et al.‚ report how one of the by-products obtained by the degradation of the maleate salt moiety is a derivate of aspartic acid [18-20]. A citizen’s petition was organised in 2002 to revoke acceptance of Amlodipine maleate as a clinically equivalent
Premium