What is Aspirin? Aspirin is on of the first drugs to ever be commonly used and is still one of the most widely used in the world. How widely used you ask? Approximately 35000 metric tonnes are produced and consumed every year. Chemically aspirin is known as acetylsalicylic acid with the chemical formula of C9H8O4. Aspirin is an analgesic‚ anti-inflammatory‚ antipyretic‚ and is an inhibitor of platelet aggregation. The history of Aspirin Aspirin has been a major part of just about everyone’s
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“Aspirin has been used for many years; it is well-understood‚ effective‚ inexpensive and widely available.” - Dr. Jeffrey Berger In the last 30 years medicines prescribed by doctors have changed beyond all recognition. Our better knowledge of the nature of diseases and their management has led to the replacement of many old remedies by new ones specifically designed for each illness. Everyone has known for years that
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Aspirin Aspirin is a salicylate‚ also known as a non steroidal anti-inflammatory drug (NSAID). It is the generic name of acetylsalicylic acid and is used clinically to treat fever‚ pain and inflammation as it works by preventing the formation of prostaglandin. Prostaglandin is the active agent that is responsible for the sensitisation at the nerve endings. It can be administered orally‚ rectally or by intravenous route. (6) Benzene ring Carboxylic acid Ester Alkane Aspirin has a pKa of 3.49
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Synthesis of Aspirin and Tylenol Kyla Wykoff Abstract Aspirin and Tylenol were synthesized by means of crystallization‚ recrystallization‚ and melting point determination. Synthesis produced significantly high percent yields for aspirin‚ however‚ produced extremely low and impure percent yields for Tylenol. A second group was also used to compare results and errors‚ in which they too were also producing extremely low percent yields of Tylenol. Therefore‚ error was based on the specific protocol
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Commercial Aspirin Tablet Analysis Tuesday Evening Intro: The purpose of this lab was to analyze commercial aspirin tablets. To do so‚ the percent acetylsalicyclic acid (active ingredient) in tablets using acid-base titration was determined‚ the percent acetylsalicyclic acid in tablets by formation of a colored iron(III)-salicylate complex was determined using spectrometry‚ and then the percents from each process was compared. Acetylsalicylic acid is produced when salicylic acid and acetic
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FOUNDATION IN SCIENCE INTRODUCTION TO PRACTICAL ORGANIC CHEMISTRY – MAKING AND PURIFYING ORGANIC COMPOUNDS Stage 1 – Deciding how much reagent to use Most organic reactions do not go to completion; most reach an equilibrium position with significant quantities of reactants still remaining. In addition‚ separating the desired product from the rest of the reaction mixture‚ and then purifying it‚ will result in the loss of more of the product. The amount of product obtained expressed as a percentage
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SYNTHESIS OF THE PHARMACEUTICAL ASPIRIN (ACETYLSALICYLIC ACID) AIM: The aim for this experiment was to synthesise a small amount of aspirin with salicylic acid as the starting product and sulphuric acid as the catalyst. The product obtained from this reaction will be impure and will need to be purified. This will be done by recrystallization. We will then record the products’ melting point and calculate the yield in order to determine the degree of purity of the aspirin sample. Diagrammatic scheme for
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and Recrystallization of Aspirin Preparation and Recrystallization of Aspirin Date of the experiment: 9 May 2013 Date of submission: 23 May 2012 Date of the experiment: 9 May 2013 Date of submission: 23 May 2012 Synopsis 1. General Objective: To familiarize with the preparation of some simple organic compound and purify the compound by recrystallization. Specific Objective: The experiment is carried out to: 1.1 Conduct the synthesis of aspirin 1.2 Reinforce the
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October 17 & October 24‚ 2012 How is Aspirin Made? This lab is about synthesizing aspirin using a hotplate to heat the reaction. It involved vacuum filtration‚ recrystallization‚ and comparing the properties of aspirin with salicylic aspirin. The first thing we did in this lab was make a hot-water bath by putting a beaker with water on a hot plate. After measuring out 2.1 grams of salicylic acid and 3 ml of acetic anhydride‚ we mixed the two together‚ along with 3 drops of sulfuric acid. We
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Experiment 7a Name: Date: Title: Purity of Aspirin by Spectrophotometry Aim: i. To measure the absorbance of different volumes of sodium salicylate solutions and aspirin with iron chloride ii. To find the concentration of each standard solutions iii. To determine percentage purity of aspirin. Abstract: The mass of acetylsalicylic acid was determined using a analytical balance. Sodium hydroxide (NaOH) was added to the acetylsalicylic acid and heated in order to hydrolyze acetylsalicylic
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