PREPARATION OF ASPIRIN AND DETERMINATION OF THE MELTING POINT Ferrer‚ Lara Melissa V. Faculty of Engineering University of Santo Tomas Manila‚ Philippines ABSTRACT This experiment involved three steps: synthesis of aspirin‚ isolation and purification‚ and the estimation of purity of the final product. The synthesis involved the reaction of salicylic acid and acetic anhydride in the presence of a catalyst‚ phosphoric acid‚ H3PO4. When the aspirin was prepared‚ it was isolated and filtered. The percentage
Premium Aspirin Acetic acid Acetic anhydride
Purity of Aspirin Objectives - To research‚ using various sources‚ the history of aspirin‚ its use in medicine‚ methods of synthesizing it and of measuring its purity - To compare the % purity of a branded aspirin tablet with a generic aspirin tablet - To compare 2 methods of composition analysis of the two types of aspirin Research
Premium Sodium hydroxide Hydrochloric acid Aspirin
Acid (ASA or Aspirin) Background Salicylic acid is a phenol as well as a carboxylic acid. It can therefore undergo two different types of esterification reactions‚ creating an ester either with the hydroxyl or with the acid. In the presence of acetic anhydride‚ acetylsalicylic acid (aspirin or ASA) is formed. Correspondingly‚ an excess of methanol will form methyl salicylate‚ which is also an analgesic. In this experiment‚ we shall use the former reaction to prepare aspirin. Salicylic
Free Aspirin Acetic acid Carboxylic acid
Synthesis of Aspirin Abstract The purpose of this experiment is to synthesize a common organic product called acetylsalicylic acid (aspirin)‚ and to become familiar with the optimum conditions needed for successful yields. Aspirin is produced from an acid catalyzed reaction between salicylic acid with acetic anhydride. The crystalline aspirin is synthesized and purified by recrystallization‚ although there is not a hundred percent yield due to sources of error. Introduction Aspirin is a medicine
Free Aspirin Carboxylic acid Acetic acid
include the development of Bayer aspirin and its’ effects. Because of Felix Hoffman’s genuine interest in his research‚ aspirin was invented‚ therefore proving beneficial to millions across the globe today. Ian Frazier connects “blue-sky” research to playing in the woods
Premium Heroin Aspirin
conduct the synthesis of aspirin‚ acquire the skills of recrystallisation using normal filtration and reinforce the technique of the melting point determination. The method used to synthesize aspirin was esterification by reacting salicylic acid with acetic anhydride with the presence of dehydrating agent‚ conc. sulphuric acid‚ to speed up the reaction. Having obtained the crude aspirin which was still impure‚ recrystallisation was conducted to remove the impurities. The aspirin harvested at the end
Free Aspirin Carboxylic acid Salicylic acid
coursework I have been investigating the synthesis of Aspirin and checking for presence and purity of Aspirin. Throughout this coursework we have looked at the history of Aspirin; industrial manufacturing; making salicylic acid; the preparation of Aspirin; recrystallization and purity; melting point; thin layer chromatography (TLC) and titration of Aspirin. I’ve learned a lot about Aspirin‚ how it works and how it is made. We found out that the Aspirin we made and used was actually very pure when we
Premium Salicylic acid Aspirin Acetic acid
Experimental Synthesis of Aspirin and Melting Point Purity Analysis Donald Yeargin CH 222‚ Section 24221 Department of Chemistry Portland Community College Portland‚ OR Abstract The various methods available to synthesize aspirin lead to the need to examine and evaluate production efficiency and purity. The purpose of our experiment was to synthesize acetyl salicylic acid (aspirin) and then determine the relative purity of the synthesized sample by observing the melting point temperature
Premium Aspirin Acetic anhydride Salicylic acid
The Synthesis of Organic Aspirin ABSTRACT: The purpose of this experiment was to find out how a reaction undergoes for a globally known painkiller called aspirin‚ and to become familiar with achieving successful yields. Aspirin is synthesized from salicylic acid and acetic anhydride. Those two chemicals are mixed together along with sulfuric acid to form a crude solid. Filtration is used separate the impurities from the crude aspirin. To get purified aspirin‚ the precipitate was heated until all
Free Aspirin Acetic acid Carboxylic acid
Cisplatin Resources 1. M. H. Hanigan and P. Devarajan‚ “Cisplatin nephrotoxicity: molecular mechanisms‚” Cancer Therapy‚ vol. 1‚ pp. 47–61‚ 2003. 2. Santiago Gómez-Ruiz‚ Danijela Maksimović-Ivanić‚ Sanja Mijatović‚ and Goran N. Kaluđerović‚ “On the Discovery‚ Biological Effects‚ and Use of Cisplatin and Metallocenes in Anticancer Chemotherapy‚”Bioinorganic Chemistry and Applications‚ vol. 2012‚ Article ID 140284‚ 14 pages‚ 2012. 3. N/A 4. Santiago Gómez-Ruiz‚ Danijela Maksimović-Ivanić‚ Sanja
Premium Chemotherapy Year of birth missing American film actors