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Summary Of Forks Over Knives

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Summary Of Forks Over Knives
Forks over Knives is a documentary detailing the global illnesses and obesity crises due to the “Western diet”. 40% of Americans are obese and over half are taking some form of prescription drug. Lipitor, a statin drug, is the most prescribed drug in the world, although there are genetic mutations many people have that are linked to statin sensitivity (1). More than 2.2 trillion dollars a year are spent on healthcare. More per person is paid on healthcare than any other industrialized country. Heart disease and cancer kill over one million Americans every year. Also chronic fatigue is an epidemic in this country. It is masked by overuse of sugar, caffeine and similar stimulants such that people are unaware of their health conditions. …show more content…
Campbell was in the Philippines trying to get protein to malnourished children. In order to keep costs down he and his colleagues decided against using animal based protein. Then Dr. Campbell discovered the more affluent families that were eating high amounts of animal based foods had children that were more susceptible to getting liver cancer. He found research supporting the effect of dietary protein on the carcinogenesis of Aflatoxin. This research conducted in India measured the carcinogenesis developing in lab rats after being fed daily doses of Aflatoxin, while being kept on a diet in high in protein and low in protein, respectively. This research paper showed a low level of milk (casein) protein to have a protective effect against liver tumors. Aflatoxins are naturally occurring mycotoxins that are produced by the species Aspergillus. Aflatoxin has a known ability to produce hepatocellular carcinoma and is one of the most carcinogenic compounds in nature (2). They are also found abundantly in plant derived foods that have been contaminated, especially in the economically developing world (2). Additionally, foods high in Glutathione help to clear the body of carcinogens (4).In a paper by Dr. Campbell, he states that AFb conjugates with GSH at the surface of a transferase (glutathione-s-transferase) in the liver, and with transferase B (ligandin) (4). Increased binding of AFb with liganin has been associated with decreased hepatocyte carcinoma …show more content…
Llaverias, G., Danilo, C., Wang, Y., Witkiewicz, A., Lisanti, M., & Frank, P. (2010). A western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer. The American Journal of Pathology, 177(6), 3180-3191. doi: 10.2353/ajpath.2010.100568
7. Carnell, S., Gibson, C., Benson, L., Ochner, N., & Geliebter, A. (2012). Neuroimaging and obesity: current knowledge and future directions. Obesity Reviews, 13(1), 44-56. doi: 0.1111/j.1467-789X.2011.00927.x
8. Chuang, J., Perello, M., Sakata, I., Osborne-Lawrence, S., Savitt, J., Lutter, M., & Zigman, J. (2011). Ghrelin mediates stress-induced food-reward behavior in mice. JCI, 121(7), 2684-2692. doi: 10.1172/JCI57660
9. Liu, B., Peto, R., Chen, Z., Boreham, J., Wu, Y., Li, J., Campbell, T., & Chen, J. (1998). merging tobacco hazards in china: 1. retrospective proportional mortality study of one million deaths. BMJ,317(7170), 1411-1422. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC28719/
10. Cao, J., Sodhi, K., Puri, N., Monu, S., Rezzani, R., Rezzani, R., & Abraham, N. (2011). High fat diet enhances cardiac abnormalities in shr rats: Protective role of heme oxygenase-adiponectin axis.Diabetology and Metabolic Syndrome, 3(37), doi:
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