Sepsis Research Paper

Maternal mortality due to sepsis is worryingly increasing through developed and developing countries. This is despite a worldwide effort towards reducing maternal death, maternal sepsis during pregnancy remains one of the worlds leading causes of preventable maternal death. In developed countries 3% of all maternal mortality is due to sepsis, whilst that figure jumps to 12% in developing countries. Pregnancy affected by severe sepsis or septci shock, run the risk of pre-term labour, fetal infect and pre-term delivery https://www.ncbi.nlm.nih.gov/pubmed/22914482 , all which run several risk in themselves.
What is the meaning of; Sepsis: Sepsis is a medical condition which happens in response to an infection. The immune system is forced into over drive which causes a release of chemicals into the blood in order to combat the infection. Microbes are released into the blood, urine, lungs, skin and other tissues throughout the body. This triggers cellular injury to the body tissues (inflammation), I the body can not regulate the immune response, it will then overwhelm the normal blood processes of the body. Sepsis can be described as an acute inflammatory response syndrome (SIRS).
Severe Sepsis: Severe Sepsis is essentially sepsis except the severe sepsis can lead to inadequate blood flow to certain parts of the body
The common sources of maternal sepsis include, urinary tract infections (pyelonephritis), pelvic structures (chorioamnionitis and endometritis), infections including pneumonia, acute appendicitis and intrauterine death just too name a few. Sepsis is generally uncommon in pregnancy, the increasing obesity rates and other pre-existing morbidities including anemia and diabetes in pregnancy are expected to add to the already increase in sepsis rates. (PPG’s) What is the pathophysiology of