Pernicious Anemia Changes
Many people around the world die from different serious diseases such as cancers and blood diseases. One of severe blood diseases is pernicious anemia. Pernicious anemia starts from gastritis, atrophy of all stomach layers, and loss of normal gastric glands. [1] then develops to the deficiency in vitamin B12, and red blood cells (Erythrocytes). In the late stage, the patient will die; however, if the disease discovers early patient can do well in treatment. To clarify the stages of developing pernicious anemia, this essay will explain the changes that occur in the body in each step. Pernicious anemia starts when stomach cannot absorb vitamin B12. In the First step, vitamin B12 enters the stomach by binding proteins that found in
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In pernicious anemia, the cells become stretch and lost the concave shape in the center, [2] which is the fourth stage. This shape contains hemoglobin, which carries oxygen, the disfiguration that occurs in the cells lead to transfer fewer amounts of oxygen. “therefore the body is deprived supplies of vital oxygen,” [3] and that is stage five. The shortage of oxygen in the cells leads to stop the metabolic processes, which is the sixth stage. Metabolism uses oxygen in interactions to form energy and uses this energy again to perform other cellular functions. Cells get energy by hydrolysis acid bonds in ATP (adenosine triphosphate) to maintain the equilibrium of ionic and osmotic. But in the seventh stage of pernicious anemia, cells do not have enough oxygen to form energy and maintain the equilibrium of ionic and osmotic. As a result, cells become uncontrolled and swelling, also main cellular components will be hydrolysis. This means the interaction within the cells will stop and the cells will die, so all body system will be stopped and the patient will die. Sometime pernicious anemia develops to another disease such as stomach cancer, also the patient will die. However, if pernicious anemia discovers early there is a high chance for the patient to live. To sum up, this essay mentions that, pernicious anemia start from some diseases in stomach lead to an inability to absorb vitamin B12. This deficiency of vitamin B12 make changes in erythrocytes shape and effect the amount of oxygen transfer, which stops metabolism and the body will
In pernicious anemia, the cells become stretch and lost the concave shape in the center, [2] which is the fourth stage. This shape contains hemoglobin, which carries oxygen, the disfiguration that occurs in the cells lead to transfer fewer amounts of oxygen. “therefore the body is deprived supplies of vital oxygen,” [3] and that is stage five. The shortage of oxygen in the cells leads to stop the metabolic processes, which is the sixth stage. Metabolism uses oxygen in interactions to form energy and uses this energy again to perform other cellular functions. Cells get energy by hydrolysis acid bonds in ATP (adenosine triphosphate) to maintain the equilibrium of ionic and osmotic. But in the seventh stage of pernicious anemia, cells do not have enough oxygen to form energy and maintain the equilibrium of ionic and osmotic. As a result, cells become uncontrolled and swelling, also main cellular components will be hydrolysis. This means the interaction within the cells will stop and the cells will die, so all body system will be stopped and the patient will die. Sometime pernicious anemia develops to another disease such as stomach cancer, also the patient will die. However, if pernicious anemia discovers early there is a high chance for the patient to live. To sum up, this essay mentions that, pernicious anemia start from some diseases in stomach lead to an inability to absorb vitamin B12. This deficiency of vitamin B12 make changes in erythrocytes shape and effect the amount of oxygen transfer, which stops metabolism and the body will