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Ovarian Cancer Research Paper

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Ovarian Cancer Research Paper
Ovarian Cancer
Teresa Barragan
English
Wednesday Session

Introduction Ovarian cancer is one of the most common types of cancer among women. It is considered to be one of the most common types of cancer of the female reproductive system. According to McGuire and Markman (2003), “despite advances in treatment over the last 40 years, ovarian cancer is the second most commonly diagnosed gynaecological malignancy, and causes more deaths than any other cancer of the reproductive system” (p. 4). Despite the fact that ovarian cancer occurs less frequently than uterine cancer, it is more aggressive and can occur at any age. In addition, it does not manifest itself in the first stages, and in most cases are diagnosed only in the later ones. All the malignant ovarian tumors are subdivided into epithelial, germ or stromal cell types (cancer). These cancers have the highest incidence among all other tumors. (Jordan, S., Green, A., & Webb, P. 2006 p.109-116).
Signs and symptoms of ovarian cancer “Ovarian cancer has often been called the “silent killer” because symptoms are not thought to develop until advanced stages when chance of cure is poor” (Goff, Mandel, Melancon, & Muntz, 2004, p. 2705). That is why the symptoms of ovarian cancer are not specific and can be disguised as other more common diseases, such as diseases of the digestive system or urinary system. The reason for the lack of clearly defined symptoms is that ovarian cancer develops in the abdominal cavity and does not cause discomfort for the patient. The main sign of the presence of most disease is a constant presence of symptoms or their worsening. For example, ovarian cancer symptoms are distinguished by their immutability of the manifestations: they progress gradually. (Goff, B. A., Mandel, L. S., Melancon, C. H., Muntz, H. G., 2004 p. 2705-2712). The main symptoms of ovarian cancer may include the following: 1. Feeling of overeating, swelling or bloating;



References: Cannistra, S.A. (2004). Cancer of the ovary. N. Engl. J. Med., 351 (24), 2519-29. doi: 10.1056/NEJMra041842 Goff, B Grilli, R., Apolone, G., Marsoni, S., Nicolucci, A., Zola, P., & Liberati, A. (1991). The Impact of Patient Management Guidelines on the Care of Breast, Colorectal, and Ovarian Cancer Patients in Italy. Medical Care, 29 (1), 50-63. Johannes, L. (2010, March 9). Test to Help Determine If Ovarian Masses Are Cancer. The Wall Street Journal. Retrieved from http://online.wsj.com/article/SB10001424052748704869304575109703066893506.html Jordan, S., Green, A., & Webb, P Jordan, S. J., Purdie, D. M., Green, A. C., & Webb, P. M. (2004). Coffee, Tea and Caffeine and Risk of Epithelial Ovarian Cancer. Cancer Causes & Control, 15 (4), 359-365. Jordan, S. J., Siskind, V., Green, A. C., Whiteman, D. C., & Webb, P. M. (2010). Breastfeeding and Risk of Epithelial Ovarian Cancer. Cancer Causes & Control, 21 (1), 109-116. Kiani, F., Knutsen, S., Singh, P., Ursin, G., & Fraser, G. (2006). Dietary Risk Factors for Ovarian Cancer: The Adventist Health Study (United States). Cancer Causes & Control, 17 (2), 137-146. King, M., Marks, J. H., Mandell, J. B. (2003). Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2. The New York Breast Cancer Study Group Science, New Series, 302 (5645), 643-646. Kuper, H., Cramer, D. W., & Titus-Ernstoff, L. (2002). Risk of Ovarian Cancer in the United States in Relation to Anthropometric Measures: Does the Association Depend on Menopausal Status? Cancer Causes & Control, 13 (5), 455-463. McGuire, W.P., & Markman, M. (2003). Primary ovarian cancer chemotherapy: current standards of care. Br. J. Cancer, 89 (3), 3-8. doi:10.1038/sj.bjc.6601494. Rossing, M. A., Tang, M. C., Flagg, E. W., Weiss, L. K., Wicklund, K. G., & Weiss, N. S. (2006). Body Size and Risk of Epithelial Ovarian Cancer (United States). Cancer Causes & Control, 17 (5), 713-720. Titus-Ernstoff, L., Rees, J. R., Terry, K. L., & Cramer, D. W. (2010). Breast-Feeding the Last Born Child and Risk of Ovarian Cancer. Cancer Causes & Control, 21 (2), 201-207. Zhang, M., Xie, X., Lee, A. H., & Binns, C. W. (2004). Sedentary Behaviours and Epithelial Ovarian Cancer Risk. Cancer Causes & Control, 15 (1), 83-89.

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