Topics: Benzodiazepine, Anticonvulsant, Seizure Pages: 1 (313 words) Published: January 14, 2013
Name of patient: GUIUAN, SYD SYHRUSAge: days oldcc: Vomiting DRUG NAME | GENERAL ACTION| SPECIFIC ACTION| INDICATION| CONTRAINIDICATION| ADVERSE EFFECTS| NURSING RESPONSIBILITY| Phenobarbital 25 mg/PPtab, 1 PPtab OD x 3 days| Barbiturate (long acting), Sedative, Hypnotic, Antiepileptic| Long-acting barbiturate. Sedative and hypnotic effects of barbiturates appear to be due primarily to interference with impulse transmission of cerebral cortex by inhibition of reticular activating system. CNS depression may range from mild sedation to coma, depending on dosage, route of administration, degree of nervous system excitability, and drug tolerance. Initially, barbiturates suppress REM sleep, but with chronic therapy REM sleep returns to normal.Phenobarbitone is a short-acting barbiturate. It depresses the sensory cortex, reduces motor activity, changes cerebellar function, and produces drowsiness, sedation and hypnosis. Its anticonvulsant property is exhibited at high doses.| Long-term management of tonic-clonic (grand mal) seizures and partial seizures; status epilepticus, eclampsia, febrile convulsions in young children. Also used as a sedative in anxiety or tension states; in pediatrics as preoperative and postoperative sedation and to treat pylorospasm in infants.| Severe renal and hepatic disorders. Severe respiratory depression, dyspnea or airway obstruction; porphyria.| Bradycardia, hypotension, syncope; drowsiness, lethargy, CNS excitation or depression, impaired judgment, hangover effect, confusion, somnolence, agitation, hyperkinesia, ataxia, nervousness, headache, insomnia, nightmares, hallucinations, anxiety, dizziness; rash, exfoliative dermatitis; nausea, vomiting, constipation; agranulocytosis, thrombocytopenia, megaloblastic anaemia; pain at inj site, thrombophlebitis (IV); oliguria: laryngospasm, respiratory depression, apnoea (especially with rapid IV admin), hypoventilation.Potentially Fatal: Stevens-Johnson syndrome.| 1)...
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