Biochem 305

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  • Topic: Folic acid, Vitamin, B vitamins
  • Pages : 2 (363 words )
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  • Published : February 9, 2013
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Assignment #1
Biochem 305

1) name| 2) name of the coenzyme| 3) RDA mg/day| 4) comm-ercial amt/2capsules | 5)deficiency disease| symptoms of deficiency| 6) problem w/ high amt| B1 Thiamin| Thiamine pyrophosphate (TPP)| 1.1| 17 mg| Beriberi| impairment of the nerves and heart muscle wasting| anaphylaxis to parenteral thiamin as well as pruritus due to allergic sensitivity to thiamin injection.| B2 Riboflavin| Flavin coenzymes| 1.1| 17 mg| rare or unobserved| inflammation of the skin, tongue, and lips; ocular disturbances; nervous symptoms| | B3 Niacin| niacinamide,nicotinamide diphosphate (NAD), and nicotinamide diphosphate hydrate (NADH)| 14| 50 mg| Pellagra| skin lesions, gastrointestinal disturbances, nervous symptoms| gastrointestinal effects for patients treated with nicotinic acid. Hepatic toxicity has been reported in patients treated medically with the vitamin.| B5 Pantothenic Acid| Coenzyme A| 1.3| 50 mg| rare or unobserved| weakness, gastrointestinal disturbances, nervous symptoms, fatigue, sleep disturbances, restlessness, nausea| | B6 Pyridoxine| pyridoxal 5’-phosphate.| 1.3| 17 mg| rare or unobserved| dermatitis, mental depression, confusion, convulsions, anemia| The critical adverse effect from high intake is neuropathy| B7 Biotin| Biocytin| 30 mcg | 200 mcg| rare or unobserved| dermatitis, hair loss, conjunctivitis, neurological symptoms| | B9 Folic Acid/Folat| folinic acid (5-formyl tetrahydrofolate)| 400 mcg/day| 533 mcg| Megaloblastic anemia| impaired formation of red blood cells, weakness, irritability, headache, palpitations, inflammation of mouth, neural tube defects in fetus| Excess folate may precipitate or exacerbate neuropathy in vitamin B12-deficient individuals.| B12 Cobalamin| methylcobalamin and adenosylcobalamin| 2.4 mcg/day| 533 mcg| Pernicious anemia| smoothness of the tongue, gastrointestinal disturbances, nervous symptoms| | Lipoate| Lipoic acid| | |...
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