Ibuprofen And Acetaminophen Research Paper
Ibuprofen and Acetaminophen
Organic chemical compounds contain a vast number of isomers, molecules with the same molecular formula but different atomic arrangement, of which there are three types: structural, geometric and optical. The most closely-linked of isomers are optical isomers, which differ only by the three-dimensional placement of the molecule’s attachments, which renders its mirror images to be non-superimposable. The presence of optical isomerism within a molecule is determined by the existence of a chiral centre—a carbon atom with four different groups (see Appendix, figure 1). Pure optical isomers have identical physical properties such as melting point, boiling point and density, as well as identical chemical properties; thus there are only two ways that they can be distinguished: their interaction with other chiral substances and their interaction with …show more content…
Ibuprofen is a drug used for anti-inflammatory purposes such as pain relief, fever and swelling reduction, and is classified as a nonsteroidal anti-inflammatory drug (NSAID). Derived from propanoic acid in the 1960s by a pharmacy chain called Boot’s UK Limited, ibuprofen was initially launched as a treatment for rheumatoid arthritis, and was awarded the Queen 's Award for Technical Achievement in 1987. It is currently available under a variety of trademarks such as Advil, Motrin, Nurofen, and Brufen, among others. Ibuprofen works by inhibiting the enzymatic action of cyclooxygenase (COX1 and COX2) within the body, which catalyzes the conversion of a compound called arachidonic acid into prostaglandins. Prostaglandins are locally-acting hormones that cause swelling, heat, loss of function, fever and pain, collectively known as inflammation, at a site of injury through the accumulation of white blood cells. Through inhibiting this reaction, painful symptoms can be reduced or
Organic chemical compounds contain a vast number of isomers, molecules with the same molecular formula but different atomic arrangement, of which there are three types: structural, geometric and optical. The most closely-linked of isomers are optical isomers, which differ only by the three-dimensional placement of the molecule’s attachments, which renders its mirror images to be non-superimposable. The presence of optical isomerism within a molecule is determined by the existence of a chiral centre—a carbon atom with four different groups (see Appendix, figure 1). Pure optical isomers have identical physical properties such as melting point, boiling point and density, as well as identical chemical properties; thus there are only two ways that they can be distinguished: their interaction with other chiral substances and their interaction with …show more content…
Ibuprofen is a drug used for anti-inflammatory purposes such as pain relief, fever and swelling reduction, and is classified as a nonsteroidal anti-inflammatory drug (NSAID). Derived from propanoic acid in the 1960s by a pharmacy chain called Boot’s UK Limited, ibuprofen was initially launched as a treatment for rheumatoid arthritis, and was awarded the Queen 's Award for Technical Achievement in 1987. It is currently available under a variety of trademarks such as Advil, Motrin, Nurofen, and Brufen, among others. Ibuprofen works by inhibiting the enzymatic action of cyclooxygenase (COX1 and COX2) within the body, which catalyzes the conversion of a compound called arachidonic acid into prostaglandins. Prostaglandins are locally-acting hormones that cause swelling, heat, loss of function, fever and pain, collectively known as inflammation, at a site of injury through the accumulation of white blood cells. Through inhibiting this reaction, painful symptoms can be reduced or