Epidermolysis Bullosa Research Paper
Epidermolysis Bullosa
2012- 2013
Overview of the disease
Epidermolysis bullosa is a distressing and painful genetic skin condition[1]. This is a rare inherited condition commonly known as Butterfly disease in Children[2]. This causes the skin layers and internal body linings to blister. There are three major forms and at least 16 to 20 subtypes which can range in severity from mild blistering to more disfiguring and life-threatening disease. Many cases of epidermolysis bullosa are often not accurately diagnosed and thus, are not reported[3].
Symptoms
The First symptoms of Epidermolysis bullosa (EB) usually shows in infancy. All forms of EB result in fluid-filled blistering and wounding of the skin. How mild/severe symptoms are depend on the type of EB. The skin blisters are in mild cases of the disease localised to specific parts of the body(e.g. palms of the hands) and heal without permanent scarring[4].More severe forms of EB can cause: blistering over large areas leading to scaring,
Skin thickening on palms and soles of the feet
Internal blistering causing swallowing difficulty, deformity of the fingernails and in the worst cases fusion of the fingers and toes[5]
Cause
There are 3 major types EB Simplex, Junctional EB and Dystrophic EB based on which layer of the epidermis separates from the deeper dermis …show more content…
The main forms of treatment are aimed at the prevention of complications and easing the discomfort of blisters. The level of treatment depends on the type and severity of the EB which is determined by examining a small sample of skin under a microscope. Different examples of treatments include puncturing blisters with a sterile needle, applying an antibiotic cream to the blister and then covering with a non-stick bandage or disinfecting the wound
2012- 2013
Overview of the disease
Epidermolysis bullosa is a distressing and painful genetic skin condition[1]. This is a rare inherited condition commonly known as Butterfly disease in Children[2]. This causes the skin layers and internal body linings to blister. There are three major forms and at least 16 to 20 subtypes which can range in severity from mild blistering to more disfiguring and life-threatening disease. Many cases of epidermolysis bullosa are often not accurately diagnosed and thus, are not reported[3].
Symptoms
The First symptoms of Epidermolysis bullosa (EB) usually shows in infancy. All forms of EB result in fluid-filled blistering and wounding of the skin. How mild/severe symptoms are depend on the type of EB. The skin blisters are in mild cases of the disease localised to specific parts of the body(e.g. palms of the hands) and heal without permanent scarring[4].More severe forms of EB can cause: blistering over large areas leading to scaring,
Skin thickening on palms and soles of the feet
Internal blistering causing swallowing difficulty, deformity of the fingernails and in the worst cases fusion of the fingers and toes[5]
Cause
There are 3 major types EB Simplex, Junctional EB and Dystrophic EB based on which layer of the epidermis separates from the deeper dermis …show more content…
The main forms of treatment are aimed at the prevention of complications and easing the discomfort of blisters. The level of treatment depends on the type and severity of the EB which is determined by examining a small sample of skin under a microscope. Different examples of treatments include puncturing blisters with a sterile needle, applying an antibiotic cream to the blister and then covering with a non-stick bandage or disinfecting the wound