Drug Study

Topics: Pharmacology, Iron, Therapeutic effect Pages: 6 (778 words) Published: March 11, 2013

Generic & Brand NamesDose, Strength & FormulationIndication/Mechanisms of Drug ActionAdverse/ Side Effects Drug InteractionNursing ResponsibilitiesRationaleClient Teaching Generic:

Ferrous Sulfate





Give FeSO4 (Sorbifer) durule OD




Other Forms:

Drops: 75 mg/0.6ml
Elixir: 220 mg/5ml
Tablets: 195 mg, 300 mg, 325 mg, 187 mg, 200 mg
Tablets (extended-release): 160 mg

Treatment for:
Iron deficient anemia
Decreased absorption of Iron
Long term bleeding
Prophylaxis of anemia
Prophylaxis of miscarriage and early birth

Mechanism of Action:

Chemical effect: Provides elemental iron, an essential component in formation hemoglobin. Therapeutic effect: Relieves iron deficiency.

Adverse Reaction:

GI: anorexia, black stools, constipation, diarrhea, epigastric pain, nausea, vomiting. Other: temporary staining of teeth (drops, suspension).


Drug-drug: Antacids, cholestryramine resin, leveodopa, tetracycline, vitamin E: May decrease iron absorption. Separate doses by 2 to 4 hours. Vitamin C: May increase iron absorption. Suggest patient take vitamin C with drug. Drug-food: Cereals, cheese, coffee, eggs, milk, tea, whole-grain breads, yogurt: May impair iron absorption. Advise against use together. Assessment:

Obtain baseline assessment of patient’s iron deficiency before starting therapy. Evaluate hemoglobin level, hematocrit, and reticulocyte count during therapy. Asses patient’s and family’s knowledge of drug therapy.


Give tablets with juice or water, but not with milk or antacids. Dilute liquid forms in juice or water, but not with milk or antacids. Don’t crush or allow patient to chew extended-release forms. Be alert for adverse reactions and drug intereactions.If patient misses a dose, tell the patient to take it as soon as he remembers but not to double the dose. Advise patient to avoid taking drug with certain foods that may impair oral iron absorption, including yogurt, cheese, eggs, milk, whole-grain breads and cereals, tea, and coffee. Teach dietary measures for preventing constipation.

Advise patient to report constipation and changes in stool color or consistency.







Give Lactulose (Duphalac ) 15 ml. OD
for 1 week.



1 week

Other forms:

Crystals for reconstitution: 10g/packet, 20g/packet
Solution: 10g/15ml, 3.33g/5mlIndications:

To prevent and treat hepatic precoma and coma in patients with severe hepatic disease. To induce bowel evacuation in geriatric patients with colonic retention of barium and severe constipation after a barium meal examination. To restore bowel movements after hemorrhoidectomy.

Mechanism of Action:

Chemical effect: Produces osmotic effect in colon. Resulting distention promotes peristalsis. Decreases blood ammonia build-up that causes hepatic encephalopathy, probably as result of bacterial degradation, which lowers pH of colon contents. Therapeutic effect: Relieves constipation, decreases blood ammonia concentration.

Adverse effects:

GI: abdominal cramps and distention, belching, diarrhea, flatulence, nausea, vomiting.


Drug-drug: Antacids, antibiotics, oral neomycin: May decrease effectiveness of lactulose. Avoid use together.Assessment:

Assess patient’s condition before starting therapy and regularly thereafter to monitor drug effectiveness. Monitor patient’s electrolyte levels during long-term use. Assess patient’s and family’s knowledge of drug therapy.


Store drug at room...
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