Generic & Brand NamesDose, Strength & FormulationIndication/Mechanisms of Drug ActionAdverse/ Side Effects Drug InteractionNursing ResponsibilitiesRationaleClient Teaching Generic:
Give FeSO4 (Sorbifer) durule OD
Drops: 75 mg/0.6ml
Elixir: 220 mg/5ml
Tablets: 195 mg, 300 mg, 325 mg, 187 mg, 200 mg
Tablets (extended-release): 160 mg
Iron deficient anemia
Decreased absorption of Iron
Long term bleeding
Prophylaxis of anemia
Prophylaxis of miscarriage and early birth
Mechanism of Action:
Chemical effect: Provides elemental iron, an essential component in formation hemoglobin. Therapeutic effect: Relieves iron deficiency.
GI: anorexia, black stools, constipation, diarrhea, epigastric pain, nausea, vomiting. Other: temporary staining of teeth (drops, suspension).
Drug-drug: Antacids, cholestryramine resin, leveodopa, tetracycline, vitamin E: May decrease iron absorption. Separate doses by 2 to 4 hours. Vitamin C: May increase iron absorption. Suggest patient take vitamin C with drug. Drug-food: Cereals, cheese, coffee, eggs, milk, tea, whole-grain breads, yogurt: May impair iron absorption. Advise against use together. Assessment:
Obtain baseline assessment of patient’s iron deficiency before starting therapy. Evaluate hemoglobin level, hematocrit, and reticulocyte count during therapy. Asses patient’s and family’s knowledge of drug therapy.
Give tablets with juice or water, but not with milk or antacids. Dilute liquid forms in juice or water, but not with milk or antacids. Don’t crush or allow patient to chew extended-release forms. Be alert for adverse reactions and drug intereactions.If patient misses a dose, tell the patient to take it as soon as he remembers but not to double the dose. Advise patient to avoid taking drug with certain foods that may impair oral iron absorption, including yogurt, cheese, eggs, milk, whole-grain breads and cereals, tea, and coffee. Teach dietary measures for preventing constipation.
Advise patient to report constipation and changes in stool color or consistency.
Give Lactulose (Duphalac ) 15 ml. OD
for 1 week.
Crystals for reconstitution: 10g/packet, 20g/packet
Solution: 10g/15ml, 3.33g/5mlIndications:
To prevent and treat hepatic precoma and coma in patients with severe hepatic disease. To induce bowel evacuation in geriatric patients with colonic retention of barium and severe constipation after a barium meal examination. To restore bowel movements after hemorrhoidectomy.
Mechanism of Action:
Chemical effect: Produces osmotic effect in colon. Resulting distention promotes peristalsis. Decreases blood ammonia build-up that causes hepatic encephalopathy, probably as result of bacterial degradation, which lowers pH of colon contents. Therapeutic effect: Relieves constipation, decreases blood ammonia concentration.
GI: abdominal cramps and distention, belching, diarrhea, flatulence, nausea, vomiting.
Drug-drug: Antacids, antibiotics, oral neomycin: May decrease effectiveness of lactulose. Avoid use together.Assessment:
Assess patient’s condition before starting therapy and regularly thereafter to monitor drug effectiveness. Monitor patient’s electrolyte levels during long-term use. Assess patient’s and family’s knowledge of drug therapy.
Store drug at room...