Ch 16

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  • Topic: DNA, RNA, DNA replication
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Biology, 7e (Campbell)
Chapter 16: The Molecular Basis of Inheritance

Chapter Questions

1) For a couple of decades, biologists knew the nucleus contained DNA and proteins. The prevailing opinion was that the genetic material was proteins, and not DNA. The reason for this belief was that proteins are more complex than DNA. This is because A) proteins have a greater variety of three-dimensional forms than does DNA. B) proteins have two different levels of structural organization; DNA has four. C) proteins are made of 20 amino acids and DNA is made of four nucleotides. D) Only A and C are correct.

E) A, B, and C are correct.
Topic: Concept 16.1
Skill: Comprehension

2) In his transformation experiments, Griffith observed that A) mutant mice were resistant to bacterial infections.
B) mixing a heat-killed pathogenic strain of bacteria with a living nonpathogenic strain can convert some of the living cells into the pathogenic form. C) mixing a heat-killed nonpathogenic strain of bacteria with a living pathogenic strain makes the pathogenic strain nonpathogenic. D) infecting mice with nonpathogenic strains of bacteria makes them resistant to pathogenic strains. E) mice infected with a pathogenic strain of bacteria can spread the infection to other mice. Topic: Concept 16.1

Skill: Knowledge

3) What does transformation involve in bacteria?
A) the creation of a strand of DNA from an RNA molecule
B) the creation of a strand of RNA from a DNA molecule
C) the infection of cells by a phage DNA molecule
D) the type of semiconservative replication shown by DNA
E) assimilation of external DNA into a cell
Topic: Concept 16.1
Skill: Knowledge

4) Avery and his colleagues purified various chemicals from pathogenic bacteria and showed that ________ was (were) the transforming agent. A) DNA
B) protein
C) lipids
D) carbohydrates
E) phage
Topic: Concept 16.1
Skill: Knowledge

5) Tobacco mosaic virus has RNA rather than DNA as its genetic material. In a hypothetical situation where RNA from a tobacco mosaic virus is mixed with proteins from a related DNA virus, the result could be a hybrid virus. If that virus were to infect a cell and reproduce, what would the resulting "offspring" viruses be like? A) tobacco mosaic virus

B) the related DNA virus
C) a hybrid: tobacco mosaic virus RNA and protein from the DNA virus D) a hybrid: tobacco mosaic virus protein and nucleic acid from the DNA virus E) a virus with a double helix made up of one strand of DNA complementary to a strand of RNA surrounded by viral protein Topic: Concept 16.1

Skill: Application

6) The following scientists made significant contributions to our understanding of the structure and function of DNA. Place the scientists' names in the correct chronological order, starting with the first scientist(s) to make a contribution.

I.Avery, McCarty, and MacLeod
II.Griffith
III.Hershey and Chase
IV.Meselson and Stahl
V.Watson and Crick

A) V, IV, II, I, III
B) II, I, III, V, IV
C) I, II, III, V, IV
D) I, II, V, IV, III
E) II, III, IV, V, I
Topic: Concept 16.1
Skill: Knowledge

7) After mixing a heat-killed, phosphorescent strain of bacteria with a living non-phosphorescent strain, you discover that some of the living cells are now phosphorescent. The best evidence that the ability to fluoresce is a heritable trait would be an observation that A) DNA passed from the heat-killed strain to the living strain. B) protein passed from the heat-killed strain to the living strain. C) the phosphorescence in the living strain is especially bright. D) descendants of the living cells are also phosphorescent. E) both DNA and protein passed from the heat-killed strain to the living strain. Topic: Concept 16.1

Skill: Application

8) In trying to determine whether DNA or protein is the genetic material, Hershey and Chase made use of which of the following facts? A) DNA does...
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