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Causes Of Sickling

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Causes Of Sickling
Sickling of the cells can lead to other symptoms such as fatigue and anaemia, dactylitis (swelling and inflammation of the hands/feet) and arthritis, bacterial infections, splenic sequestrations (sudden pooling of the blood in the spleen) and liver congestion, lung and heart injury and aseptic necrosis. Normal haemoglobin cells are smooth and round in shape like the letter "O." These cells flow freely within the blood vessel. Abnormal haemoglobin cells deform like the letter "C," losing oxygen and clot together blocking the blood flow and stopping the movement of a healthy, normal, oxygen-carrying blood.
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