DNA – basic features, base composition
RNA basic features, base composition, what are all the different types of RNA? Nucleotide - what makes up one? What is it’s general structure? Mendel- basic concept of heredity, punett squares, genotype vs. phenotype, homozygous, heterozygous, what is an allele, dominant allele recessive allele Two general classes of genetics and what makes up each one
Relationship of a gene to locus to allele to chromosome
What organisms do we do research on? Why? Eukaryotes? Prokaryotes? Basically all definitions in bold print
Timeline of the search of genetic material- all of the scientists involved, their experiments, the conclusion of their experiments Composition and structure of purines and pyrimidines (sugar, bases, phosphate groups, role of phosphodiester bonds, bonds between bases) Experiments and scientists responsible for the discovery of the structure of DNA (Chargraff, Franlin, Wilkins, Watson Crick) Features of the DNA double helix
Compacting DNA in chromosomes- role of topoisomerases, looping,supercoiling Role of histones and non-histones, chromatin, euchromatin, heterochromatin, what is a nucleosome? histone core? C value & C value paradox
Centromere and telomere, what are they- how are they similar? How are they different? What is their importance? CEN sequences, importance of A-T rich regions, what is their purpose? All bold faced definitions
3 models for DNA replication, the experiment that proved semiconservative was right, the scientists who performed it and how they did it? All elements and machinery necessary for replication: origin, replicator, template strands, helicase, DNA gyrase, DNA primase, primosome, RNA primers, SSB proteins, Okazaki fragments, leading and lagging strands, DNA ligase, continuous, discontinuous, replication fork, replisome. Pol I, pol III, free dNTPs How do we replicate the ends of chromosomes? Why is this important? What is telomerase? Why is it...