Biochem Syllabus

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SYLLABUS
BCHM 100A: INTRODUCTION TO BIOCHEMISTRY
FALL 2012
Instructor:

Emily Westover, westover@brandeis.edu
Kosow 108, ext. 6-2304
Office Hours: M 11-1, W 1-2, or by appointment

Assistants:

Vy Nguyen, vnguyen@brandeis.edu
Rick Roy, rroy@brandeis.edu
Chris Wilson, cwilson@brandeis.edu

Meetings:

Lecture 10:00 – 10:50 am, MWH, location TBA
Recitation 7:30 – 9:20 pm, H, location TBA

Textbook:

Lehninger Principles of Biochemistry by Nelson and Cox, 4th or 5th Ed.

Learning Objectives
Students in BCHM 100a will:
 explain biological phenomena using chemical concepts;
 recognize the relation between protein structure and function;  describe and predict metabolic pathways;
 communicate biochemical concepts in writing.
Students will demonstrate achievement of these learning objectives through:  5 Problem Sets (25 pts. each, lowest score will be dropped)  2 Midterm Exams (100 pts. each) **Midterm exams will be given during the recitation period (7:30 – 9:20 p.m.) on Thursday, October 11 and Thursday, November 8.**  Final Exam (150 pts., ½ cumulative, ½ new material) **The final exam is scheduled for Friday, December 21 at 9:15 a.m -12:15 p.m. Do not make travel arrangements that interfere with the scheduled final exam.**

Students can earn up to 15 pts. of extra credit for participation. At the instructor’s discretion, points will be awarded for the following: (1) sharing answers in class, (2) posting questions or answers to the LATTE forum, or (3) contributing news articles for the “Biochemistry Beat.” Policies

 I will not accept any late assignments. If you will be away when an assignment is due, turn it in early or submit it on time electronically.
 I will only consider re-grade requests if (1) the request comes within 1 week of the assignment return date and (2) the graded assignment is accompanied by a typed, brief explanation for the request.

 I expect students to stay apprised of course information given in class and via LATTE.  I expect all students to follow the university’s policies on academic integrity (see Brandeis’ Student Affairs website).

 I request any student with a documented disability on record with the University wishing to have a reasonable accommodation made in this class to contact me immediately.

Fall 2012 BCHM 100a Schedule (subject to change)
Date
Topic
Sections in Lehninger
Other
1
H 8/30 Introduction
1.1-1.3
*No Recitation
Monday, September 3: No Class
2
W 9/5
Water, weak interactions
2.1
3
H 9 /6
Acid/Base Equilibria
2.2
Recitation
4
M 9/10 Acid/Base Equilibria
2.3
5
W 9/12 Amino Acids, Peptides
3.1
6
H 9/13
Protein Structure
3.2-3.4
Recitation
Monday, September 17: No Class
7
W 9/19 Protein Structure
4.1-4.2
PS #1
8
H 9/20
Protein Structure
4.3-4.4
*No Recitation
9
M 9/24 Protein Structure: Mb
5.1
Wednesday, September 26: No Class
10
H 9/27
Protein Function: Mb
5.1
Recitation
Monday, October 1: No Class
11
W 10/3
Protein Function: Hb
5.1
PS #2
12
H 10/4
Protein Function: Hb
5.1
Recitation
Monday, October 8: No Class
13
*T 10/9* Protein Function: Hb
5.1
14
W 10/10 Enzymes
6.1
15
H 10/11 EXAM REVIEW
730 pm MIDTERM #1
16
M 10/15 Enzymes
6.1-6.4
17
W 10/17 Enzymes
6.1-6.4
18
H 10/18 TBD
*No Recitation
19
M 10/22 Sugars
7.1
PS #3
20
W 10/24 Fats, Nucleotides
10.1–10.2, 8.1-8.2
21
H 10/26 Carbonyl chemistry
13.2
Recitation
22
M 10/29 Coenzymes
Various pages
23
W 10/31 Coenzymes
Various pages
24
H 11/1
Metabolism
13.1-13.4
Recitation
25
M 11/5
Metabolism
13.1-13.4
PS #4
26
W 11/7
Glycolysis
14.1-14.3
27
H 11/8
EXAM REVIEW
730 pm MIDTERM #2
28
M 11/12 Citric Acid Cycle
16.1, 16.2
29
W 11/14 Citric Acid Cycle
16.1, 16.2
30
H 11/15 Pentose P, Gluconeogenesis 14.4-14.5
Recitation
31
M 11/19 Case Study: Supermouse
JBC. 2007,282:32844
Wednesday and Thursday, Nov 23 and 24: No Class, No Recitation 32
M 11/26 FA Catabolism, PLP...
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