Krabbe Disease Research Paper

The common signs and symptoms in the early stage of Krabbe Disease are; feeding difficulties, extreme irritability, declined alertness, muscle spasms, excessive crying, fever with no sign of an infection, loss of head control, frequent vomiting and delays in normal development. As the disease progresses over time, the symptoms become more intense; increased loss of hearing and sight, seizures, a stiff, fixed posture, increased loss of ability to breathe and swallow, stiff muscles and loss of developmental abilities---Krabbe disease mainly occurs in individuals within the first six months of life, which is early infantile Krabbe disease. This type is the most severe and infants are vulnerable. Later Onset Infantile Krabbe disease is the second