Upon doing research on the disease I learned that Alzheimer's disease is perhaps the most common form of dementia, although several others exist. Alzheimer’s disease is a progressive disease of the brain. In the early stages, people experience some memory loss which progresses to marked memory loss, then to a decrease in thinking ability such as decision making. Later the disease leads to the loss in the ability to perform activities of daily living or recognize loved ones. The changes in the brain that often mirror the decline in thinking are the development of plaques and tangles in the brain. These changes may begin in areas of the brain associated with memory, but later spread more widely throughout the brain. The plaques and tangles can lead to a gradual loss of connections between brain cells and eventually cell death.…
Addison’s disease, according to Mayo Clinic, is a disease cause by a insufficient amount of hormones that come from the adrenal gland. Typically what is found in individuals with Addison’s disease is a limited amount of cortisol along with limited amounts of aldosterone also.i Adrenal crisis also occurs when there is not enough cortisol in the body, on a more dangerous level.v It usually occurs when the adrenal gland is damaged severely or Addison’s disease is not treated properly.v…
ALX is caused by a mutation in the GFAP (Glial fibrillary acidic protein) gene on chromosome 17. Molecules of this protein bind together to form intermediate filaments which are used to support and strengthen cells. The mutation causes a structural alteration in GFAP which impairs the formation of normal intermediate filaments and they collect in cells called astrocytes. Astrocytes are non-neuronal glial cells that provide biochemical support to endothelial cells that form the blood-brain barrier, provide nutrients for nervous tissue and maintenance of extracellular ion balance etc. This leads to the formation of Rosenthal fibers in the astrocytes, abnormal clumps of GFAP. Therefore no nutrients are provided to the oligodendrocytes and as a result myelin is slowly degenerated.…
Aarskog syndrome (also known as Aarskog–Scott syndrome, faciodigitogenital syndrome, shawl scrotum syndrome and faciogenital dysplasia) is a rare autosomal X-linked inherited disorder that affects a person's height, muscles, skeleton, genitals, and appearance of the face. It mostly affects at birth and the symptoms usually become apparent by the age of 3years. Unfortunately, Aarskog syndrome is a lifelong condition without a cure. Some people with Aarskog syndrome are born with more serious abnormalities, such as heart defects or a cleft lip with or without an opening in the roof of the mouth (cleft palate). Most males with Aarskog syndrome have a shawl scrotum, in which the scrotum surrounds the penis. Less often, they have undescended testes (cryptorchidism) or a soft out-pouching around the belly-button (umbilical hernia) or in the lower abdomen (inguinal hernia).…
Addison's disease is a disorder of the adrenal glands. It is also known as hypocortisolism or adrenal insufficiency. The disease occurs when your adrenal glands do not produce sufficient amounts of certain hormones. The adrenal glands do not produce enough cortisol and more often than not, insufficient amounts of aldosterone.…
In Alzheimer’s disease, two abnormal proteins build in the brain. They form clumps called either “plaques” or “tangles”. These plaques and tangles interfere with how brain cells work and communicate with each other. The plaques are usually first seen in the area of the brain that makes new memories.…
Adrenoleukodystrophy is a deadly genetic disorder that affects mostly boys and men. ALD is determined when the myelin sheath that surrounds the neuron is deteriorated, damaged or simple not formed, and it is not carrying properly the neurological messages that sends the brain to the body, because there is an accumulation of saturated very long fatty acids as an immune response, our body stops moving or responding as a consequence.…
Alzheimer’s is caused by broken signals within the brain leading to the death of brain cells, this can also lead to a shortage of some important chemicals, these chemicals control the transmitting of messages to the brain.…
Alzheimer 's disease is a disease that slowly and little by little destroys brain cells. It is neither transmittable nor contagious, but is the single most common cause of dementia. A condition that affects about 10 percent of those aged over 65 and about 20 percent of those aged over 75.…
In 1901, Dr. Alois Alzheimer began observing a patient named Auguste D. Auguste began behaving more and more bizarrely after developing an intense suspicion about her husband. She would hide objects, become lost in her own home, start screaming loud insisting that people were out to murder her. Dr. Alzheimer found Auguste confused lines when she read, repeated single style labels many times when she wrote and used odd phrases when she spoke. When Auguste died in 1906, Dr. Alzheimer performed an autopsy on her brain. The autopsy revealed damage and cell death had shrunk the tissue. The nerve cells contained a “tangled bundle of fibrils”. From this observation Dr. Alois termed the disease after himself calling it Alzheimer’s disease. Tangles and plaques are the 2 most important pathological features of Alzheimer’s disease.…
Neurodegenerative diseases is a common cause of dementia which means that the brain cells known at the neurons either are degenerating therefore the neuron die off quicker than that of the neurons of a normal aging processes. This will lead to a more decline in the persons mental health such as memory, language and sometimes their physical abilities all depending on which area of the brain is infected. These neurodegenerative diseases are known to us as Alzheimer’s, fronto-temporal dementia, and Lewy bodies are where over time a build up of abnormal protein deposits in the brain cause the gradual change and damage to the neurons which will cause the shrinkage of the brain. Dementia is anything which affects the brain and the loss of function of the brain in such a way that the things we normally take for granted for e.g. our ability to remember things such as time, date, events, to place ourselves in a location to use words, to use language all of these things begin to disappear.…
Krabbe disease is a disorder inherited from parents, which destroys the myelin coat of nerve cells throughout the nervous system and the process is called demyelination. Demyelination inhibits the transmission of nerve impulses and that hinders the communication of the brain and the body and that results in disability (Mayo Foundation for Medical Education and Research, 2016). Dr. Knud. H.Krabbe diagnosed this disorder in 1916 (Arizona Board of Regents, 2015). Krabbe disease is a body recessive disorder that results from lack of enzyme galactorebrosidase or simply GALC, which is necessary to break down and metabolize toxic substances in nerve tissues (YouTube, 2016). A lack in GALC results in toxic built-up for example psychosine which is a destructive toxin that accumulates in the brain, as it begins to build-up in the nerve tissue it destroys the myelin sheath which covers the nerves (YouTube, 20160.…
This illness however is still nowhere near fully understood. There are however a number of different types of dementia and their causes which have been identified in the above. Alzheimer’s is caused by two abnormal proteins that build up into the brain; they form either ‘plaques’ or ‘tangles’. These plaques and tangles interfere with how the brain responds and how the cells work to communicate with each other, the plaques are usually seen in the area were the brain makes new memories there is ongoing research for finding new ways to stop these proteins so they can protect the brain cells from harm. Whereas vascular dementia is the reduction in the blood flow to the brain, the blood carries essential oxygen and nourishment that the brain needs to survive and without it the brain cells can die. The vessels that carry the blood around the body is called the vascular system, there are many ways that these vassals in the brain can be damaged causing vascular dementia such as:…
Alzheimers - is a physical disease that affects the brain. There are nore than half a million people in the UK with the disease. Alzheimers is progress when a build up of proteins in the brain lead to a loss of connection between the nerve cells. This itself causes the death of these nerve cells and the loss of brain tissue. People with alzheimers also suffer from a shortage of chemicals in their brain. Thesse chemicals are used to transmit signals around the brain. Where there is a shortage the signals are not transmitted effectively. This causes the person to have confusion over places and time and also issues with thinking and memory loss.…
Alzheimer's is a disease of the brain that causes a loss in memory. This results in dementia, loss of brain functions (thinking, remembering, and reasoning) severe enough to interfere with everyday life. When German physician, Alois Alzheimer, first described the disease in 1907, it was thought to be rare. Today, Alzheimer's disease is the most common cause of dementia, affecting 10% of people 65 years old, and nearly 50% of those age 85 or older. An estimated four million Americans have Alzheimer's. Alzheimer's disease usually begins gradually, causing a person to forget recent events and to have difficulty performing familiar tasks. How quickly the disease advances differs from person to person, causing confusion, personality and behavior changes, and impaired judgment. Communication becomes difficult for Alzheimer's patients. They struggle to find words, finish thoughts, or follow directions. Eventually, people with Alzheimer's become unable to care for themselves.…
