introduction on clinical biochemistry INTRODUCTION Homeostasis mechanism of human body will regulate the osmotic pressure of the blood. This function is carried out by the kidneys‚ that will filter blood and produces urine through three stages: ultrafiltration‚ reabsorption and secretion. The end product of the process will produce urine‚ which contains mainly water and a range of substances that such as inorganic salts‚ organic compounds and some metabolites. The quantity and composition of the urine
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P4: Explain the role of the kidney in the homeostatic control of water balance P5: Explain dysfunction in relation to water balance and possible treatments M3: Discuss dysfunction in relation to water balance and possible treatments D2: Analyse the impact on the human body of dysfunctions in relation to water balance For P4‚ I’m going to outline the physiological overview of the kidneys and then I am going to explain the renal system. Also I am going to explain the kidneys in more detail.
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Nephron * Basic structural and functional unit of kidney * Regulate concentration of water and soluble substances * FUNCTION: Eliminates waste‚ regulates blood pressure‚ regulates blood PH‚ controls levels of electrolytes and metabolites A. Urine Formation FILTRATION - plasma filtered from glomerulus into Bowman’s capsule * Blood pressure forces filtrate through filtration slits between podocytes of Bowman’s capsules. * Approx 20% of blood plasma is non-selective filtered
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Column chromatography 2. Density gradient centrifugation 3. Electrophoresis 4. enzymatic digestion 5. Removal of small ions or molecules or to exchange one ionic environment for another during purification is done by : Dialysis‚ Ultrafiltration and Gel filtration Dialysis-addition of NaOH and HClm PROTEIN STRUCTURES 1. Fibrous –not water soluble: Collagen 2. Globular- mostly water soluble : Globulin‚ Hemoglobin and Albumin-Globular A. Invertase- catalytic protein or enzyme
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pastoris was concentrated by ultrafiltration using a Vivaspin (GE Healthcare‚ UK) membrane filter with a 10 kDa molecular weight cut-off‚ and directly used for the enzymatic hydrolysis of SCB. The interaction between the three recombinant enzymes for SCB hydrolysis was performed with different
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Homeostasis A state of balance in the body Whoa Homeostasis “the tendency of a system‚ esp. the physiological system of higher animals‚ to maintain internal stability‚ owing to the coordinated response of its parts to any situation or stimulus tending to disturb its normal condition or function” - Dictionary.com Unabridged (v 1.1) “The ability or tendency of an organism or a cell to maintain internal equilibrium by adjusting its physiological processes.” - American Heritage Stedman’s Medical
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“Dialysis is the artificial process of eliminating waste (diffusion) and unwanted water (ultrafiltration) from the blood.” (Christian Nordqvist). To reach this goal‚ the patients at the MSJMC are treated for three sessions a week‚ three (3) to four (4) hours continuously with keen eye on the water treatment plant. The water treatment plant is computerized
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Excretion in Humans Excretion is the removal of toxic materials‚ the waste products of metabolism and substance in excess of requirements from organisms. Metabolism is chemical reactions taking place inside cells‚ including respiration. The body excretes three main waste materials. These are Carbon Dioxide‚ Urea and Water. Excretion is a very important feature to us because without it toxic substances will build up in our bodies and kill us. It also helps in maintaining the composition of body
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|Dialysis Practice Area |% of Test | |A. Clinical |50% | |B. Technical |23% | |C. Environment |15% | |D. Role |12%
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Urinary system Homeostasis Salt provides two elements that are essential for life and for good health - sodium and chloride ions. They are both elements that the body cannot manufacture itself so it must be supplied by food. Although salt is the most common dietary source for these essential elements‚ sodium also available from various foods that contain sodium naturally. Sodium is a mineral element that plays a critical role in body physiology. It controls the volume of fluid in the body and
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