Diseases of the Muscular System There are over 650 muscles in the human muscular system. Each muscle has a specific role to perform. These muscles help us talk‚ walk‚ sit‚ run‚ eat‚ move about‚ hold things‚ and most important the continuous pumping of the heart muscles keeps us alive. Muscular system diseases cause many problems in the human body‚ that affects the mobility and functioning of various parts of the body. The list is very long as there are number of disorders that affect the human body
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Rabies life cycle. According to the World Health Organization the death rate of rabies exceeded 50‚000 every year globally considering unreported cases1. Rabies virus is associated with bats mostly‚ and it mainly exists in rabid animal saliva1. Rabies can enters a body through a direct contact such as bite transmission‚ a bite from a rabid animal‚ or nonbite transmission‚ saliva or central nervous system tissue touches an open wound or scratch on the body1. These are the most common ways that allows
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Myasthenia gravis Overview: Myasthenia Gravis is an autoimmune disorder of the post-synaptic neuromuscular junction whose pathogenesis consists in an attack on antibody-mediated At the acetylcholine receptor site on the postsynaptic membrane of the neuromuscular junction. Causes: Characteristics of the disease are muscle weakness and fatigue. The pattern of symptoms is typically fluctuating; it is more pronounced at night and improves with rest. Initial symptoms include: ptosis‚ diplopia or blurred
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Botulism is a dangerous neuroparalytic illness caused by a botulinum toxin that is a product of the Clostridium botulinum bacteria. This toxin invades neuromuscular junctions by blocking the release of acetylcholine and results in lack of muscle contraction. According to Centers for Disease Control and Prevention‚ “There are three main kinds of botulism: foodborne botulism‚ infant botulism‚ and wound botulism. Foodborne botulism occurs when a person ingests the toxin within food that leads to illness
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Overview Snake venom is the poison fluid normally secreted by venomous snakes when biting. It is produced in the glands‚ and injected by the fangs. Snake venom is used to immobilize and/or kill prey‚ and used secondarily in defence. It is a clear‚ viscous fluid of amber or straw colour. There are two main types of venom produced by snakes‚ containing primarily either: *Neurotoxins - these attack the nervous system. *Hemotoxins - these attack the circulatory system. While most snakes’ venom contains
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The Tired Swimmer Case Study Go to this Website: http://www.sciencecases.org/tired_swimmer/tired_swimmer.asp Answer the Following Questions for Parts IIV. Part I: 1. What vital signs or symptoms does Annie exhibit? Fatigue‚ blurred vision‚ eye strain‚ shortness of breath‚ loss of control over muscles 2. Can you see any common features in Annie’s signs and symptoms? All relate to nervous system 3. Why is Annie having problems breathing? She was walking up flights of stairs 4. What
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level relating signs‚ symptoms and initial collaborative management in relation to the case study outlined in appendix one. Organophosphate poisoning essentially affects transmission of impulses at the neuromuscular junction (Porth‚ 2002). Transmission of impulses at the neuromuscular junction is mediated by the release of the neurotransmitter actycholine at pre- and post ganglionic parasympathetic‚ and pre- ganglionic sympathetic and somatic nerves (Murray‚ Daly‚ Little‚ Cadogan‚ 2007). Acetylcholine
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of axon depolarization to individual muscle fibers via motor units. Each motor unit has so many number of motor nerves that extend to individual muscle fibers by way of a neuromuscular junction called the synapse. When the motor nerve is depolarized‚ acetylcholine is released from the axon terminals at the neuromuscular junction. . The acetylcholine binds to the receptor sites on the motor end plate membrane. The neurotransmitter‚ acetylcholine‚ increases the motor end plate’s permeability to
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Viany Reyes November 08‚ 2011 Dr. Dunaway Neuronal signaling in muscle contraction is triggered when an action potential reaches the neuromuscular junction. At this junction‚ acetylcholine (ACh) is the main neurotransmitter. Packaged in vesicles‚ ACh fuses with the neuron’s membrane and is released into the synaptic cleft. ACh diffuses toward the motor end plate and bind to the neurotransmitter receptor on it. The muscle fiber is then triggered to produce an action potential of its own
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-Understand the difference between Sarcolemma and T-tubules -Know the difference between thick and thin filaments (actin vs. myosin) -Know all the components of a sarcomere ( each band‚ zone‚ & line) -Understand the neuromuscular junction and the components of the neuromuscular junction (synaptic knob‚ motor end plate‚ synaptic cleft) -Know what happens at each physiological event of muscle contraction. (understand what occurs at each event) -Know the difference between repolarization vs depolarization
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