Abstract Sickle-cell disease is a genetic disorder that results from the abnormal structure of red blood cells. The peculiar shape of the red blood cell prevents the normal absorption of oxygen. This disease results from the abnormal production of hemoglobin S (HbS). Therefore‚ a mutation in this gene causes a lower supply of oxygen to the cells‚ which results in occlusion of the blood vessels. Individuals diagnosed with sickle-cell anemia have abnormal function of the gene that encodes for subunit
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Sickle Cell Anemia‚ also known as Sickle Cell Disease‚ is a disease that causes the production of abnormal hemoglobin. The red blood cells (RBCs) carry oxygen to organs and tissues. Hemoglobin‚ a molecule in the RBCs‚ is a protein that attaches to the oxygen in the lungs and carries it to all parts of the body. Hemoglobin takes on the oxygen‚ and releases carbon dioxide‚ a process known as oxygenation. In the tissues‚ deoxygenation occurs where the processes is reversed‚ when hemoglobin releases
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The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin’s‚ Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels‚ less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged.This is what causes the problems of sickle
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Sickle cell anemia Sickle cell anemia is a disease found right here in America‚ but in low levels compare to most of the world. The rate for disease is around five times greater in certain places in Africa. Sickle-Cell Anemia is often referred to as the “Negro-Inherited” disease‚ but that is incorrect. Although African Americans have a high occurrence of Sickle-Cell Anemia (1 in 400 African Americans)‚ many other nationalities suffer from the disease. Sickle-Cell Anemia affects 8 out of 100‚000
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SICKLE CELL ANEMIA Dillon Lukacs Normal Circulatory system In a normal circulatory system blood flows easily through the veins and arteries. Oxygen is delivered throughout the body to all the vital organs. Sickle Cell Disease An anemia is a condition where there are less red blood cells than normal. Sickle cell anemia is a disorder where the body creates sickle or crescent shaped red blood cells. In a normal blood cell they look like donuts with a hole in the middle. This shape helps them
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done on the genetic causes of Sickle Cell Anemia and how it developes‚ as well as it’s effects on the circulatory‚ muscular‚ and respiratory systems‚ as well as it’s effects on the joints and other systems of the body‚ and the complications associated with them. Most of the research has been done to explore on the reasons why it mostly effects the African-American community and people who are from the West Coast of Africa. It has also been known that Sickle Cell Anemia also effects people from the
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For Sickle Cell Anemia The definition for sickle cell anemia is an abnormal‚ rigid‚ sickle shape. Sickling decreases the cells flexibility and results in a risk of various complications. Sickle cell is the name of a specific disease in which there is a homozygosity for the mutation that causes Hbs. This type of disease‚ usually presenting in childhood‚ occurs more commonly in people from parts of the tropical and sub-tropical regions where malaria is more common. If a person has sickle cell
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Sickle Cell Disease: Journal Article Review Kelsey Bowman Bio 204: Anatomy and Physiology 2 Zellers Sickle cell disease is an autosomal recessive genetic disorder most common in African Americans‚ which results from a mutation affecting the amino acid sequence of the beta chains of hemoglobin molecules in red blood cells. The abnormal hemoglobin which causes the red blood cells to sickle is called hemoglobin S. Sickling occurs when the red blood cells are deoxygenated causing
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Sickle Cell Anemia Sickle cell anemia is an inherited blood disease. The word anemia is defined as meaning that the blood does not have the required number of red blood cells. These cells take on a crescent shape‚ which is where the disease takes its name from the abnormal sickle shapes of the cells. It is commonly found in people from Africa‚ the Mediterranean region‚ southern India and the Middle East. “This disease of the blood was first discovered in 1910 in a black college student from the
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Sickle cell anemia is a disease that changes normal round red blood cells into cells that are shaped like crescent moons. Sickle cell comes from a farm tool with a curved blade. Sickle cells get stuck and block blood vessels which stop the oxygen from getting through. This causes a lot of pain and can also harm organs‚ muscles‚ and bones. Sickle cell is a lifelong battle that causes pain‚ infection‚ anemia‚ and even a stroke. Sickle cell is an inherited disease. It used to be that when people were
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