toxicity. Once transported to the liver‚ enzymes break down parent drug into less biologically active forms that are less toxic to the body in a process known as biotransformation. This process also makes drugs more suitable for excretion by the kidneys. During the biotransformation process toxic reactive chemicals or intermediate chemicals may be formed in the liver‚ which have
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SGLT2 is a transporter responsible the reabsorption of glucose that is localized in the kidney. SGLT2 is responsible for 90 % of glucose reabsorption in the proximal tubule. Canagliflozin‚ Dapagliflozin‚ and Empagliflozin inhibits the reabsorption of glucose by the kidney and excretes glucose in the urine. This improves glycemic control. Pharmacodynamics Each of the three drugs has similar effects in improving glycemic control
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Rifampicin - a semisynthetic compound derived from Amycolatopsis rifamycinica In 1957‚ a soil sample from a pine forest on the French Riviera was brought for analysis to the Lepetit Pharmaceuticals research lab in Milan‚ Italy. There‚ a research group headed by Prof. Piero Sensi (1920-) and Dr. Maria Teresa Timbal (1925 - 1969) discovered a new bacterium. This new species appeared immediately of great scientific interest since it was producing a new class of molecules with antibiotic activity. Because
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P3- Outline the gross structure of all the main body systems Cardiovascular system Purpose- the purpose of the cardiovascular system is to carry blood throughout the body. To carry to the organs and other areas of the body that needs it. To carry gaseous wastes to the respiratory system so that is can get rid of them Main organ- heart‚ blood vessels‚ blood. The heart is one of the most important organs in the entire human body. It is really nothing more than a pump‚ composed of muscle which
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HS111 Unit 6 Assignment- Progress Report In this Assignment you will proofread the Progress Report listed below. Next‚ you will identify the 10 mistakes that are listed in the report. The mistakes could be misspellings‚ incorrect abbreviations‚ or misuse of a medical term. Please list them in the chart below under the heading “Medical Terminology Error.” After you have listed the errors‚ you will need to identify the correct term or abbreviation. Please list them in the chart below under the heading
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Question 1 (a) Name the following: (i) The phase of cardiac cycle in which the auricles contract. Systole (ii) The organ where urea is produced. Liver (iii) The hormone that helps increase the reabsorption of water from the kidney tubules. ADH (iv) Chemical substances produced by micro organisms that can kill or inhibit the growth of other micro organisms. [4] (b) State the main function of the following: (i) Chordae tendinae It holds the valves of the heart in place. (ii) Lymphocytes
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dependent upon a You correctly answered: b. hydrostatic pressure gradient. 3. The filtrate You correctly answered: d. All of these answers are correct. 4. An important place that filtration takes place in the body is in You correctly answered: d. the kidneys. 010/04/12 page 1 Experiment Results Predict Question: Predict Question 1: What effect will increasing the pore size of the filter have on the filtration rate? Your answer : c. The filtration rate will increase. Predict Question 2: What
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c. Describe the path that urine takes to exit the body‚ starting in the kidney. Urine collects in the kidneys travels through 2 thin tubes Ureters to bladder Muscles in the ureter walls tighten and relax to push urine downward away from the kidneys Sphincter is like a rubber band which keeps the opening of the bladder so that urine can pass down through the urethra urethra‚ tube that allows urine exits the body. 4. Discuss your dissection of the components of the endocrine system of the
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Aldosterone‚ what it is and why it is important? Aldosterone is a hormone produced and released from the adrenal glands above the kidneys. Its role is to increase the reabsorption of sodium ions from the loop of Henle and Distal tubule to conserve sodium in the blood and body fluids. When sodium ions enter the blood from the distal tubule‚ water follows by osmosis‚ which increases blood volume and blood pressure. If there is an increased blood volume and blood pressure from high salt concentrations
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Society or (ACS) bladder cancer is the 6th most common cancer in the United States. They approximate that over 54‚300 people will be diagnosed in 2014 and cause more than 12‚400 deaths. The purpose of your urinary bladder is to store urine from the kidneys. Bladder cancer has a very high percentage of coming back once you are in remission with a 75% chance that new tumors will develop again. Normally the first thing that you notice when you have bladder cancer is blood in your urine‚ other warning signs
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