sciatic nerves‚ which have been previously used in vitro and in vivo. This will be assessed using microscopy‚ which will track the nerve using ultrasound imaging of targeted areas to assess risk of pressure related trauma. Also‚ the nerves will be electrically stimulated to observe the functional performance of the microbuble exposure [4]. Specific Aim 2 will apply focused ultrasound to specific static nerves using optical control in vivo. Electrical stimulation will be used for muscle stimulation
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Secondary excitotoxicity is thought to be more relevant to chronic neurodegenerative disorders than the classical acute form. In this pathway increased glutamate levels are not required as disturbances with the neuronal resting membrane potential cause glutamate receptors to be over-activated by physiological levels of glutamate. In a neuron which is affected by another pathological process and shows reduced ATP production‚ Na+ dysfunction or impaired glucose metabolism and as a result has an abnormal
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Dr. J. Chris Sackellares Biography Dr. J. Chris Sackellares was born in Savannah‚ received his bachelors in Chemistry at the University of Georgia in 1970‚ and his MD at the Medical College of Georgia. He completed his rounds as an intern in the department of Internal Medicine at the University of Louisville in ‘74‚ and then his residency in neurology ‘77. He also at the University of Virginia he trained in Epilepsy and Clinical Neurophysiology. He is a certified Psychiatrist and Neurologist
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Comparative Analysis of How Prospects and Perspectives of Tissue Engineering Have Evolved Over the Years The concept of engineering living beings is not new to us. Tales of mythical creatures and beasts have long been interwoven with our history and form an essential part of many cultures all over the world. However as a science‚ tissue engineering is thought to be quite young. It evolved as a concept and term in the late 1980s. And although some research was undertaken in that field‚ it was only
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Keloid Scar Treatments: Successful keloid treatment has still been an obstacle because the current treatments are far away from guarantying cure of the disease and preventing recurrence. This probably due to the lack of an extensive research to study and evaluate those treatments (Gauglitz et al.‚ 2011). There are a wide range of therapies that have been used in treating keloid and hypertrophic scars. Although most of the therapeutic options that we will cover work for both scars‚ we have to be very
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Abortion: Killing a Human Being Topic: The ethics behind the practice of abortion and validating it as a murder Specific Purpose: To inform students of the scientific procedure of abortion and paralleling it to the killing of a human being‚ just in vivo (during conception). INTRODUCTION *ask class question‚ give disclaimer* Attention Materials: Mention the story of a Philadelphian doctor who committed wrongful abortions. Segue into the the fetus from conception to its first few moments to the legal
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Received 15 December 2005 Accepted 16 February 2006 abstract Objectives: To review current knowledge of tooth whitening with respect to external bleaching methods. Data: The scope is the external bleaching of vital teeth and focuses on mechanisms; in vivo and in vitro measurement methods‚ and factors influencing the efficacy of the whitening process. Keywords: Tooth colour Tooth whitening Mechanism Measurement Peroxide Aesthetics Sources: ‘‘Medline’’ and ‘‘ISI Web of Science’’ databases from 1966
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. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387 1.5 Basic Fibroblast Growth Factor (bFGF) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387 2. In Vivo Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 388 2.1 IGF-1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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highly porous with an interconnected pore network for cell growth and #ow transport of nutrients and metabolic waste; (ii) biocompatible and bioresorbable with a controllable degradation and resorption rate to match cell/tissue growth in vitro and/or in vivo; (iii) suitable surface chemistry for cell attachment‚ proliferation‚ and di!erentation and (iv) mechanical properties to match those of the tissues at the site of implantation. This paper reviews research 2000 Elsevier Science Ltd. All rights on the
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problem. Although myriad factors have been implicated in impaired wound healing‚ recent research has focused on the role of matrix-based bacterial communities called biofilms that are often associated with chronic wounds. Various in vitro and in vivo models have been developed to study the role of biofilms in non-healing wounds. Basic science and clinical studies suggest that effective eradication of pathogenic biofilms requires multimodality strategies including serial debridement‚ systemic
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