Attention should be paid to possible cross-reactivity of certain drug groups. Data have been reported regarding genetic predisposition to drug hypersensitivity reactions‚ which are strongly associated with the major histocompatibility complex. (11) The pathogenesis of SJS/TEN is not fully understood. But it is believed to be immune-mediated‚ furthermore‚ keratinocyte apoptosis followed by necrosis is
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Acute renal failure is the sudden loss of the kidneys ability to function; affecting more than 100‚000 people in the United States alone each year (NIDDK‚ 2008). This paper will discuss the basic pathophysiology of acute renal failure‚ including its cause‚ disease mechanisms‚ symptoms‚ some of the treatments and pharmacological therapies. Pathophysiology Acute renal failure (ARF) is the rapid loss of kidney function occurring when high levels of uremic toxins accumulate in the blood
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Choice “D” is the best answer. This patient’s regimen includes tenofovir. Tenofovir disoproxil is an antiretroviral medication used to prevent and treat HIV/AIDS and to treat chronic hepatitis B. Tenofovir can cause acute renal failure‚ Fanconi syndrome‚ proteinuria‚ or tubular necrosis. These side effects are due to accumulation of the drug in proximal tubules. Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTIs). NRTIs interrupt the HIV replication cycle via competitive inhibition
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Solitary confinement is completely detrimental to juveniles‚ especially on their mental development. Placing juveniles in solitude has been linked to psychological and physical harm on the development of youths incarcerated. According to Elizabeth Rademacher (2016)‚ studies demonstrate that solitary confinement of youth correlates with high rates of suicide‚ depression‚ and future criminal activity (p. 1026). The mind of a child continues to maturation until they are about twenty years old and placing
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Class | Drugs | MOA | Indications | Contraindications | Drug Effects/Interactions | Adverse Rxns | Unique | Beta1 Adrenergic Sympathomimetics | Dopamine/Intropin (neurotransmitter/catecholemine) | * Dopamin is the only receptor to stimulate these site * A precursor in synthesis of NE * Action: Beta agonist/alpha agonist- dose dependentDopaminergic | * Dilate renal blood vessels‚ brain‚ mesentery and heart vessels increased blood flow * Stimulate alpha/beta receptors/vasoconstrictor
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soremouth‚ nausea‚ vomiting‚ diarrhea‚ abdominal pain‚ bloody diarrhea‚ enterocolitis‚ pseudo membranous colitis‚ nonspecific hepatitis * GU: Nephritis * Hematology: Anemia‚ thrombocytopenia‚ leukopenia‚ neutropenia‚ prolonged bleeding time * Hypersensitivity: Rash‚ fever‚ wheezing‚ anaphylaxis * Local: Pain‚ phlebitis‚ thrombosis * Other:Superinfection | * Assess patient for infection (vital signs‚ wound appearance‚ sputum‚ urine‚ stool‚ and WBCs) at beginning and through out therapy. *
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APPENDICITIS Case study Patient name: J.K Sex: Male Race: Fijian Age: 47 Personal History Mr. J.K is married with four children. He describes himself as a socialable person likes to explore new things. Occupation: He works at the Nasinu Town Council as a Carpenter Family History: -his father is a known diabetic patient and his grandmother died of leukemia -his paternal uncle had died from septicemia. Social History: Cigarettes 1 pack per week x 12years now; he stopped smoking
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slows down when there isn’t enough sufficient oxygen being carried to the blood. Each White Blood Cell and its Function: a) Lymphocyte – major combatant in immune responses b) Basophil – intensifies the inflammatory reaction‚ is involved in hypersensitivity reactions c) Monocyte – phagocytosis and cell debris cleanup d) Neutrophil – active in phagocytosis e) Eosinophil – releases enzymes that fight the effects of histamine and phagocytize antigen-antibody complexes Leukocytes in person infected
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degenerative illness that disturbs the outflow of air which goes in and out of the lungs‚ and it affects all people of all ages. This essay will discuss the definition and the distinct types of asthma‚ intrinsic and extrinsic. Asthma is a type III hypersensitivity and a common long-lasting disorder that affects the lungs‚ especially the bronchi. In the early 400’s‚ most of people were suffering from a mysterious disease which was identifies by its symptoms: serious coughing‚ breathlessness‚ and wheezing
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Bronchitis Bronchitis is an inflammation of the mucous membranes of the bronchi (the larger and medium-sized airways that carry airflow from the trachea into the more distal parts of the lung parenchyma).[1][2][3] Bronchitis can be divided into two categories: acute and chronic.[1][2][3][4] Acute bronchitis is characterized by the development of a cough or small sensation in the back of the throat‚ with or without the production of sputum(mucus that is expectorated‚ or "coughed up"‚ from the respiratory
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