Dopain Synthesis Essay

Class | Drugs | MOA | Indications | Contraindications | Drug Effects/Interactions | Adverse Rxns | Unique | Beta1 Adrenergic Sympathomimetics | Dopamine/Intropin (neurotransmitter/catecholemine) | * Dopamin is the only receptor to stimulate these site * A precursor in synthesis of NE * Action: Beta agonist/alpha agonist- dose dependentDopaminergic | * Dilate renal blood vessels, brain, mesentery and heart vessels increased blood flow * Stimulate alpha/beta receptors/vasoconstrictor, increase CO2 improves contractility of the heart also can cause renal dilation. Drug of choice for shock | | * Tx circulatory shock, heart failure and ↓ BP * Monitor for: Dysrhythmias * ↑ HR * Chest pain
(Proventil, Ventolin) | * Short-acting, selective, β2-adrenergic receptor agonist (bronchodialator) | * Sx relief during maintenance * Asthma * Emphysema * Acute/Chronic Bronchitis * Anaphylaxis | | Tachycardia , heart palpitationShakiness, nervousness Hyperkinesias * Overactive, restlessness, agitation * N/V * Aggression * Fluid retention and swelling * Xerostomia (dry mouth) * Hyperactivity * Hypertension * Increased Appetite * Insomnia * Nervousness * Flushing * Nightmares * Nosebleed * Rash * Throat irritation * Agitation * Anxiety * Excitement * Headache | | * Protection against exercise-induced asthma * Used as relief of acute asthmatic attack * Administered – Orally/inhalation * Metered dose inhaler, nebulizer, tablets, and syrup * Monitor allergies * Can induce hypokalemia
Anticholinergic Drug | Atropine (Antimuscarinic)Tolterodine (Detrol)Ipratropium(Atrovent)Oxybutynin(Ditropan)Dicyclomine(Bentyl)Scopolamine (Dramamine) | Block the action of Ach (heart, respiratory tract, GI tract, skin’eyes, urinary bladder exocrine glands | ↑ HR Dilates pupils (mydriasis) ↑IOP↓ Gastric acid & intestinal motility CONSTIPATIONsalivationDRY MOUTHTremors and spasticity GU system: ↓ bladder contraction urinary retention (Antispasmodic) Bronchial dilation Ipratropium (Atrovent)↓ bronchial secretions↓ salivationContraindicated hx glaucoma | Treat Peptic ulcer/ GI hypersecretionIrritable bowel disease (diarrhea)Bronchospasms, COPD, IncontinenceParkinson DiseaseGiven Preoperatively to decrease salivation and GI secretions to prevent aspiration | Known drug allergyNarrow angle glaucomaMyasthenia gravisAcute cardiovascular instabilityGI or GU tract obstruction | ↑ heart rate CNS excitation Drowsiness with ↑ dosesDilated pupilsPhotophobia Blurred visionDifficult urinationUrinary retentionDry mouth and eyesDecreases GI and Respiratory secretionsConstipationIntolerance to heat |