Pain Management and Quality of Life for Sickle Cell Disease Patients Cynthia Evans Mississippi College Pain Management and Quality of Life for Sickle Cell Disease Patients This is a review of literature examining how frequent recurring episodes of pain affect the quality of life in the sickle cell disease patients. Several studies conducted concerning pain management and quality of life for sickle cell disease patients indicate additional studies needed. Identifying additional effective
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1. Macromolecules affected by Sickle Cell a. Hemoglobin: When the body is infected by Sickle Cell Disease‚ the primary structure of Hemoglobin is mutated. In the amino acid sequence‚ valine is substituted for glutamic acid causing sickle cell disease. This single mutation will eventually cause the entire protein to divide itself. b. Lipids: The lipids in the membrane of the cell are altered by sickle cell disease. Those who suffer from the disease have defective fasting lipid metabolism. This has
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Conclusion 1 Based on what you know about blood‚ why would having a sickle cell anemia crisis result in a reduced red blood cell count‚ an elevated white blood cell count‚ and a reduced hematocrit? There’s a reduced RBC count‚ elevated WBC count‚ and a reduced hematocrit because of the shape of the RBC. The sickle cell anemia causes the RBC to have a different shape; a crescent and rigid shape and there are not a lot of them. So because of that‚ there’s more WBC and a reduced hematocrit. Also‚ the
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Case Study 97 1. Sickle cell disease is a group of disorders that affects hemoglobin‚ the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S‚ which can distort red blood cells into a sickle‚ or crescent‚ shape. SCD affects millions of people worldwide‚ particularly those with African‚ Spanish‚ Mediterranean‚ and Indian ancestry. Some 120‚000 infants are born with SCD every year worldwide
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Defects Sickle Cell Anemia (SCA) Sickle Cell Anemia (SCA) is one of a group of diseases collectively termed hemaglobinopathies‚ in which normal adult hemoglobin is partially or completely replaced by abnormal sickle hemoglobin(HgbS). Sickle Cell Anemia includes all of those hereditary disorder‚ the clinical‚ hematologic‚ and pathologic features of which are related to the presence of HbgS. Also know as SS and homozygous sickle cell disease. The most common form of SCD are: Sickle Cell Anemia
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Anemia is a deadly disease; approximately 50% of people with sickle cell anemia survive to mid-40’s although fewer than 10% live more than 60 years. The devastating thong about anemia is that it can be inherited and with no cure‚ the cases of Anemia are increasing. Even though there is no cure‚ early diagnosis of low blood count can lead to better treatment‚ with better treatment‚ patients can live normal lives. However‚ the key to early diagnosis is learning what anemia is and the causes of this
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Anemia Anemia is usually defined as a decrease in amount of red blood cells (RBCs) or the amount of hemoglobin in the blood. It can also be defined as a lowered ability of the blood to carry oxygen. When anemia comes on slowly the symptoms are often vague and may include: feeling tired‚ weakness‚ shortness of breath or a poor ability to exercise. Anemia that comes on quickly often has greater symptoms which may include: confusion‚ feeling like one is going to pass out‚ and an increased desire to
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Anemia ABSTRACT The purpose of this paper is to briefly describe the initial core diagnostic questioning and core set of diagnostic testing related to the patient presenting with anemia. Subjective information and recommended testing are written with consideration of the scope of practice of the family nurse practitioner. In addition‚ three specific case studies are examined. Anemia Core set of subjective questions The healthcare provider should initially obtain a history of any previous
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Anemia A blood type is a classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells (RBCs). These antigens may be proteins‚ carbohydrates‚ glycoproteins‚ or glycolipids‚ depending on the blood group system. Some of these antigens are also present on the surface of other types of cells. Some of these red blood cell surface antigens can stem from one allele and collectively form a blood group system. It is called The ABO system and it
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families with a history of the autosomal recessive disease Sickle cell anaemia should have all embryos screened with Pre-Implantation Genetic Diagnosis technology (PGD). If tested positive‚ treatment should be made compulsory for the child at a young age and will be treated with stem cell gene therapy. This disease has no personal relevance to me‚ however‚ there is currently 90K people suffering from Sickle cell anaemia in the United States. Sickle cell anaemia is relevant to society because it greatly
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