5 Computational Virtual Screening Towards Designing Novel Anticancer Drugs Po-Yuan Chen1‚2 1Department of Biological Science and Technology‚ China Medical University‚ Taichung‚ Taiwan‚ 2Brain Research Centre‚ University of British Columbia‚ Vancouver‚ 1Republic of China 2Canada 1. Introduction Generally speaking‚ Docking is most popular and critical issue in this research field‚ because it contains most important information both Ligands (Drugs) and Receptors (it can be intracellular protein
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Micropower Energy Harvesting Abstract More than a decade of research in the field of thermal‚ motion‚ vibration and electromagnetic radiation energy harvesting has yielded increasing power output and smaller embodiments. Power management circuits for rectification and DC–DC conversion are becoming able to efficiently convert the power from these energy harvesters. This paper summarizes recent energy harvesting results. Introduction The low power consumption of silicon-based electronics
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IB Chemistry Summary- By Paul Li & Silvia Riggioni TABLE OF CONTENTS Table of Contents............................................................................................................................................................ 1 Atomic Theory................................................................................................................................................................ 3 The Electromagnetic Spectrum.............................................
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8.2 Chemical Earth 8.2.1 The living and non-living components of the Earth contain mixtures * Construct word and balanced formulae equations of chemical reactions as they are encountered Combustion reaction (burning) element + oxygen → oxide e.g. 4Na (S) + O2 (g) → Na2O (s) Reaction with hydrogen element + hydrogen → hydride e.g. Ca (s) + H2 (g) → CaH2 (s) Reaction between an oxide and water metallic oxide + water → hydroxide * metallic oxide is also known as “basic oxide” e.g
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MODULE 1: THE CHEMICAL EARTH 3.1.1: Elements in Earth are present mostly as compounds because of interactions at the atomic level * Identify that matter is made of particles that are continuously moving and interacting Matter: anything that has mass and occupies space. Exists in three different states: solid (s)‚ liquid (l) and gas (g) The Particle Theory: “All matter is made up of small‚ indivisible particles called atoms that are continuously moving” | Solid | Liquid | Gas | Particle
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affinity for oxygen. 1c) Cooperativity is a key feature of the haemoglobin when exposed to oxygen; this is shown when the globin units of deoxyhaemoglobin are tightly held by electrostatic bonds in a conformation with a relatively low affinity for oxygen. The binding of oxygen to a heme molecule breaks some of the electrostatic bonds between the globin subunits‚ leading to a conformation change that leaves the remaining oxygen binding sites more exposed‚ thus the binding of one oxygen molecule to deoxyhaemoglobin
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THE CHEMICAL EARTH: 1. The living and nonliving components of the Earth contain mixtures ● Construct word and balanced formulae equations of chemical reactions as they are encountered Reactants → products Chemical reaction: the way atoms are joined changes‚ atoms are not created nor destroyed‚ but are rearranged Indicators: emission of light or heat‚ odour formation of a gas formation of a precipitate colour change change in state aqueous = dissolved in water‚ an aqueous solution
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A chemical bond is an attraction between atoms that allows the formation of chemical substances that contain two or more atoms. The bond is caused by the electromagnetic force attraction between opposite charges‚ either between electrons and nuclei‚ or as the result of a dipole attraction. The strength of chemical bonds varies considerably; there are "strong bonds" such as covalent or ionic bonds and "weak bonds" such as dipole-dipole interactions‚ the London dispersion force and hydrogen bonding
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Safety Precautions and Lab Procedures Bret Niemeyer Abstract—The purpose of this paper is to provide you with safety precautions‚ lab procedures and reference materials to equip you with useful information in the computer electronics and technology fields. The topic is not complete‚ however it should introduce concepts and provide a framework of where to obtain important information for your safety and well-being. shut down of instruments. I. INTRODUCTION HIS DOCUMENT examines safety precautions
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only one of the two atoms involved in the reaction‚ then it’s called dative covalent bond. It is represented by a short arrow going from the electron giving both electrons towards the one providing neither. 2.1 Metallic bond is a strong electrostatic attraction between a
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