Differential diagnose 1: Sickle Cell Anemia A 17-year-old African American female presented to the clinic with the following symptoms‚ chest and abdominal pain‚ and jaundice eyes. Her vital signs revealed B/P 98/50‚ pulse 112‚ respiration. 28 and temp. 99.9. EKG and chest x-ray completed with the result within normal range. She was discharged‚ and within four hours returned to the ER. Sickle cell disease is defined as a group of heredity disorder characterized by abnormal hemoglobin‚ called hemoglobin
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Adams 1 Dwayne Adams Instructor: Croshaw Medical Terminology 1 18‚ April 2013 Sickle Cell Anemia Sickle-cell Anemia is a genetic blood disorder caused by the presence of an abnormal form of hemoglobin molecules in which the red blood cells loose their disc-shape and become crescent shaped. The shape also known as “hemoglobin S”. unlike normal red cells which are usually smooth and malleable‚ tend to collect after releasing oxygen‚ and cannot squeeze through small blood vessels. The
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Pernicious Anemia and its association to orthostatic hypertension Pernicious anemia is the major form of vitamin B12 deficiency. It is caused by serum antibodies against intrinsic factor which leads to B12 deficiency rather than by B12 deficiency itself. Absorption of vitamin B12 requires intrinsic factor which is secreted by parietal cells. Pernicious anemia is marked by autoimmune attack on gastric mucosa and a loss in parietal cells. Approximately 75% of the affected patients have type I antibody
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Introduction - sickle cell anemia The first suggestion that genes might provide the information for all proteins came from Linus Pauling’s lab at Caltech. He and his student Harvey Itano studied hemoglobin‚ the protein in red blood cells that transports oxygen from the lung to metabolically active tissues‚ like muscle‚ where it is needed. In particular‚ they focused on the hemoglobin of people with sickle-cell disease‚ also known as sickle-cell anemia‚ a genetic disorder common in Africans‚ and
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Sickle cell anemia is a genetic disease that affects the shape and functionality of red blood cells. It is caused by a mutation in the DNA of the protein‚ hemoglobin‚ specifically in the beta chain. There are 531 base pairs in this DNA strand. Substitution or point mutation occurs‚ causing “GAG” to become “GTG”. This results in valine being created instead of glutamate. The mutation causes the hemoglobin to cling together in low oxygen levels and the red blood cell changes shape‚ preventing it from
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Sickle Cell Anemia first came into the view of the world around 1910 when Dr. James Herrick; a cardiologist‚ had a patient who complained of pain and described symptoms that sounded like anemia. He handed the case down to his assistant who‚ after taking a blood sample‚ discovered that the patient’s blood cells were not shaped like normal blood cells. When the patient’s blood cells were compared to normal blood cells‚ they appeared to be “sickle shaped”. After seeing this for himself Dr. Herrick took
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Critical Care Nursing: Sickle Cell Anemia Critical Care Nursing 10/15/2009 Sickle cell anemia affects millions of people worldwide. Sickle cell anemia is a disease in which your body produces abnormally shaped red blood cells. They don’t last as long as normal‚ round red blood cells‚ which leads to anemia. Sickle cells contain abnormal hemoglobin that causes the cells to have a sickle shape. Sickle-shaped cells don’t move easily through your blood vessels. They’re
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Congenital Spherocytic Anemia‚ also known as Hereditary Spherocytosis is a rare blood condition I have had since my birth and this is why I wanted to research it. A lot of people have a hard time understanding what this condition is and what effects it has on a person; it requires a lot of in depth information to get a full understanding. Hereditary Spherocytosis is a red blood cell disorder which changes the shape of the cells to be spherical‚ which causes a lot of complications. The Outcome was
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Erythrocyte count = 3.1 x 10/mm RBC smear showed microcytic and hypochromic cells Reticulocyte count = 1.5% Other laboratory values were within normal limits. Question Considering the circumstances and the preliminary workup‚ what type of anemia does Ms. A most likely have? In an essay of 500-750 words‚ explain your answer and include rationale. Case Study #2 Mr. P is a 76-year-old male with cardiomyopathy and congestive heart failure who has been hospitalized frequently to treat CHF
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What Are Nutritional Deficiencies? The recommended daily amount (RDA) of a nutrient is determined by how much the body needs to stay healthy. Nutrients can be obtained in a variety of ways—from eating a varied diet to taking vitamin supplements. A nutritional deficiency occurs when the body doesn’t absorb the necessary amount of a nutrient. Deficiencies can lead to a variety of health problems‚ such as problems of digestion‚ skin problems‚ stunted or defective bone growth‚ and even dementia. What
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