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Vitamin C and Collagen

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Vitamin C and Collagen
INTRODUCTION

What is collagen ?
Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendon, ligament and skin, and is also abundant in cornea, cartilage, bone, blood vessels, the gut, and intervertebral disc. Certain collagens found in skin tissue are essential for skin strength and elasticity. Over time, this collagen breaks down, causing skin to lose its suppleness and begin to wrinkle and sag. (Perumal, S. et.al., 2008)
There are many types of collagen fillers like Bovine collagen, Autologen, Isolagen and Dermalogen. (Tholpady A. et.al., 2011) Dermalogen is human collagen. (Bailey J.B. et.al., 2001) While Bovine collagen implants are temporary fillers and their use has been associated with major adverse side effects. Approximately 3% of patients experience an allergic reaction to injected bovine collagen with development of circulating antibodies to the foreign material. Therefore, skin testing is no guarantee of compatibility. (Gilchrest B.A. et.al., 2006)
What is vitamin C ?
Vitamin C or L-ascorbic acid or L-ascorbate is an essential nutrient for humans and certain other animal species. (Sebastian J. et.al., 2003) Vitamin C is a water-soluble vitamin that is necessary for normal growth and development. It aids in collagen production and reduces fine lines & wrinkles. Collagen loss and disorganisation is part of the process of ageing, leading to skin sagging and wrinkle formation. On the other hands, vitamin C may include protection against immune system deficiencies, cardiovascular disease, prenatal health problems, eye disease, and even skin wrinkling. (Zelman K.M. et.al., 2011)
Vitamin C is needed for the growth and repair of tissues in all parts of your body. It is used to form an important

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