Damaged cardiac tissue will have long term effects on overall cardiac function and right now if cardiac tissue becomes necrotic there is no guaranteed recovery of the tissue. Although studies are being done to explore possibilities in regenerating new cardiac cells to replace the damaged cells. Since 1956 experimenting with multiple types of stem cells have resulted in various amount of outcomes in improving cardiac function. Stem cell therapy has not yet been perfected and still have unanswered questions in the procedure of administrating therapeutic amounts of stem cells, the best route in delivery of the stem cells, and how long proper admission should consist of. As well the controversy of the use of embryotic stem cells still …show more content…
The way a hair cell knows to become a hair cell is through a genetic code known as DNA. That being said when your heart is being develop myocyte cells are what makes up the myocardium because within the cell the genetic code instructs the cell to grow as myocardial tissue. As well there are genetic instructs that tell the cells when to stop growing myocardial tissue this genetic protein is known as TGFB-1 which is responsible for control of growth and division of myocyte …show more content…
Concerns regarding intracoronary delivery are that with this route the cells that are administered have a potential to cause a blockage in the coronary arteries which would further damaged the myocardium. Further concerns with stem cell therapy are that instead of enhancing neovascularization are that a formation of myoma or tumor would be the result. If the stem cells become infected or contaminated and are injected into the heart the potential for the patient to develop endocarditis or myocarditis (inflammation of the endocardium or myocardium) can be a devastating consequence. Major concerns about the dosage, and timing of the stem cells are still unclear and many questions are still