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Recrystallization

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Recrystallization
RECRYSTALLIZATION
Lem Therese D. Delos Ama, Glenn Dale M. Desquitado, John Carlos M. Drapesa,
Arianne Valerie B. Escritor, Elisha Ellis R. Esteva
Group 4 2B Medical Technology Organic Chemistry Laboratory

ABSTRACT
In this experiment, acetanilide was used as the pure organic compound. Acetylation of aniline and acetic anhydride yields the crude product or crude acetanilide. The crude acetanilide was purified by dissolving it in hot water and then the solution was cooled slowly by placing in an ice bath. The yielded crystals were pure acetanilide since molecules of other compounds present in the crude acetanilide were excluded from the growing crystal lattice. Lattice is a fixed and rigid arrangement of atoms, molecules or ions. The melting point of the pure acetanilide was then determined by placing it in a capillary tube then immersed it to the oil bath with a thermometer and was monitored. The percentage yield calculated was 37.04%.

INTRODUCTION Recrystallization is the simplest and most widely used operation for purifying organic solids that differ in their solubility at different temperature. The objectives of this experiment are to purify an impure solid, and calculate its percentage yield. It is a way of effective recovery of a substance mixed with another to produce a pure compound. With their differences in solubility you can separate them by dissolving the mixture then filter out the impurities in the process.

In this experiment, aniline is the primary compound used to acquire Acetanilide, which is our product. Anilineor phenylamine(IUPAC name) with a formula of C6H5NH2, is an odorless, oily, poisonous benzene derivative.

Figure 1. Structure of Aniline

Acetanilide is the product of this recrystallization. Acetanilide or N-phenylacetamide (IUPAC name) with a formula of C6H5NH(COCH3) is produced by adding acetic anhydride with Aniline.

Figure 2. Structure of Acetanilide

The experiment’s objectives are the



References: Ault A. (1983). Techniques and Experiments for Organic Chemistry Fourth Edition. 7 Wells Avenue,Newtown, Massachusetts, USA.: Allyn and Bacon Inc. Pp. 44-61. Lehman, J.W. (2009). Operational Organic Chemistry A Problem-Solving Approach to the LaboratoryCourse Fourth Edition. Upper Saddle River, New Jersey, USA. Paerson Education, Inc. Pp. 692-706 Recrystallization (n.d) http://science.csustan.edu/russell/Courses/Chem3012/Lab%20Procedures/Recrystallization.pdf Recrystallization (n.d.) http://www.chem.umass.edu/~samal/269/cryst1.pdf Recyrstallization Formal Report (n.d) http://www.termpaperwarehouse.com/essay-on/Recrystallization-Formal-Report/54228 Wigal C. (n.d.) Purifying Acetanilide by Recrystallization. Lebanon Velley College.http://www.cerlabs.com/experimen ts/1087540703X.pdf

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