Quantitative Study Critique Summary
Quantitative Study Critique: Most Effective Cutaneous Antisepsis for Prevention of CVC Infection
S. Student
Grand Canyon University: NSR 433
May 31, 2013 Quantitative Study Critique: Most Effective Cutaneous Antisepsis for Prevention of CVC Infection
Introduction
This is critique of a randomized controlled trial study in relation to catheter-related bacteremia as the most frequent complication of the central venous catheter (CVC). The purpose of the study is to decide whether the use of 0.5% tincture of chlorhexidine or 10% povidone-iodine solution, is the most beneficial for preventing CVC exit site colonization, significant catheter tip colonization and catheter-related bacteremia in ICU patients.
Protection of Human Participants
Risks and Benefits Human subjects are necessary in research and must be treated with respect. The authors of this study did not address the actual risks and or benefits of being involved as a participant of this study. However, two citations in the introduction, referencing chlorhexidine as better than povidone-iodine for preventing infections and …show more content…
The catheter insertion sites were inspected every 72 hours for signs of erythema and purulent drainage. If erythema and purulent drainage were present, it was considered an “exit site infection” (Humar et al, 2000). Upon removal of the CVC the catheter tip was cultured. Catheter-related sepsis was determined if the organisms on the catheter tip matched organisms in the patients bloodstream. During dressing changes of the CVC, “quantitative exit-site cultures”(Humar et al, 2000) were taken from the skin around the insertion site. To maintain uniformity in culturing at the site, a 5cm by 5cm template was placed over the insertion site to allow an exact area within which to swab for bacteria. Bacteremia was defined by a single positive blood
S. Student
Grand Canyon University: NSR 433
May 31, 2013 Quantitative Study Critique: Most Effective Cutaneous Antisepsis for Prevention of CVC Infection
Introduction
This is critique of a randomized controlled trial study in relation to catheter-related bacteremia as the most frequent complication of the central venous catheter (CVC). The purpose of the study is to decide whether the use of 0.5% tincture of chlorhexidine or 10% povidone-iodine solution, is the most beneficial for preventing CVC exit site colonization, significant catheter tip colonization and catheter-related bacteremia in ICU patients.
Protection of Human Participants
Risks and Benefits Human subjects are necessary in research and must be treated with respect. The authors of this study did not address the actual risks and or benefits of being involved as a participant of this study. However, two citations in the introduction, referencing chlorhexidine as better than povidone-iodine for preventing infections and …show more content…
The catheter insertion sites were inspected every 72 hours for signs of erythema and purulent drainage. If erythema and purulent drainage were present, it was considered an “exit site infection” (Humar et al, 2000). Upon removal of the CVC the catheter tip was cultured. Catheter-related sepsis was determined if the organisms on the catheter tip matched organisms in the patients bloodstream. During dressing changes of the CVC, “quantitative exit-site cultures”(Humar et al, 2000) were taken from the skin around the insertion site. To maintain uniformity in culturing at the site, a 5cm by 5cm template was placed over the insertion site to allow an exact area within which to swab for bacteria. Bacteremia was defined by a single positive blood