Preimplantation Genetic Diagnosis
Integrating biological knowledge to develop an informed response to a socio-scientific issue.
The use of IVF and preimplantation genetic diagnosis (PGD)
Preimplantation genetic diagnosis (PGD) is the process of identifying genetic defects within an embryo before implantation, PGD allows the embryos DNA to be studied for mutations and genetic diseases. Originally PGD was used on female embryos and was used to prevent pregnancy termination in pregnancies with high risks of a sex linked genetic disease.
Process
The IVF procedure consists of ovarian stimulation, egg retrieval, egg fertilization, embryo development, and embryo transfer. Ovarian stimulation is needed to produce multiple eggs, laboratory tests are conducted to monitor the eggs. …show more content…
This hyperstimulation can occur in women using IVF and PGD. Excess hormone medication in the body can lead to ovarian hyperstimulation (OHSS),where the ovaries become inflamed and swollen. Small numbers of women could develop severe OHSS, which can cause weight gain, lower abdominal pain, nausea and even death. About 1-2% of women experiencing ovarian stimulation develop severe ovarian hyperstimulation. Ovarian Hyperstimulation can cause a loss in pregnancy and increases the risk of miscarriages.
Social Risks
Some of the social risks linked to PGD are emotional strain and the cost of the PGD procedures. IVF/PGD is not a guaranteed way to conceive a child, eggs that are retrieved may all be unhealthy and not suitable for fertilization while the chance of getting pregnant with IVF is 37% and a 35.5% delivery rate. The excess hormones in the woman's body and the risks of IVF being unsuccessful may have a great strain on a women's mental health . Finding a unwanted genetic condition in the embryo can result in the tough decision of whether the parents will terminate the pregnancy which can be mentally tolling on the parents and physically tolling on the women.The cost is another factor that has a great effect on the parents as screening is expensive, one cycle of PGD costs around $12,000 NZD. This is a cost that many can not afford and could
The use of IVF and preimplantation genetic diagnosis (PGD)
Preimplantation genetic diagnosis (PGD) is the process of identifying genetic defects within an embryo before implantation, PGD allows the embryos DNA to be studied for mutations and genetic diseases. Originally PGD was used on female embryos and was used to prevent pregnancy termination in pregnancies with high risks of a sex linked genetic disease.
Process
The IVF procedure consists of ovarian stimulation, egg retrieval, egg fertilization, embryo development, and embryo transfer. Ovarian stimulation is needed to produce multiple eggs, laboratory tests are conducted to monitor the eggs. …show more content…
This hyperstimulation can occur in women using IVF and PGD. Excess hormone medication in the body can lead to ovarian hyperstimulation (OHSS),where the ovaries become inflamed and swollen. Small numbers of women could develop severe OHSS, which can cause weight gain, lower abdominal pain, nausea and even death. About 1-2% of women experiencing ovarian stimulation develop severe ovarian hyperstimulation. Ovarian Hyperstimulation can cause a loss in pregnancy and increases the risk of miscarriages.
Social Risks
Some of the social risks linked to PGD are emotional strain and the cost of the PGD procedures. IVF/PGD is not a guaranteed way to conceive a child, eggs that are retrieved may all be unhealthy and not suitable for fertilization while the chance of getting pregnant with IVF is 37% and a 35.5% delivery rate. The excess hormones in the woman's body and the risks of IVF being unsuccessful may have a great strain on a women's mental health . Finding a unwanted genetic condition in the embryo can result in the tough decision of whether the parents will terminate the pregnancy which can be mentally tolling on the parents and physically tolling on the women.The cost is another factor that has a great effect on the parents as screening is expensive, one cycle of PGD costs around $12,000 NZD. This is a cost that many can not afford and could