EXPLORING THE MEANING OF PREGNANCY
AMONG FILIPINO COLLEGE STUDENTS
A Research Proposal
Presented to
The Faculty of the College of Nursing
Our Lady of Fatima University
In the Fulfillment of the
Requirements of the Degree
Bachelor of Science in Nursing
by:
Ariel A. Abeleda
Laarnie S. Chan
Cristy A. Laureta
Joan R. Mapilis
Kierwin P. Mariano
Ralph Roger R. Nicolas
Justin Jake C. Ortega
Maridel P. Placido
Archie P. Santos
BSN 3Y3-11
CHAPTER 1
The Problem and It’s Background
Introduction
The first and known systemic sign of the existence of a variable embryo prior to implantation is the presence of a lymphocyte modifying activity which is detectable in maternal serum within hours of fertilization. The study of this so called “early pregnancy factor” activity has generated considerable interest in the field of reproductive biology due not only to the potential to develop, extremely early methods of pregnancy detection but also to monitor embryo viability prior to implantation.
An objective assessment of the basic observation can only be interpreted as “EPF” activity expression being due to the action of a complex system. As such a new paradigm has been proposed by Clarke to explain the capacity of pregnancy. Briefly, it has been proposed that all blood serum contain inherently active low molecular weight moieties, and in addition possess the capacity to stimulate the production of even more when applied to the lymphocytes to the rosette inhibition assay.
The present studies extend this model by defining the role of thioredoxin in the “EPF” phenomenon with site directed the production genetic change studies determining the molecular features of the thioredoxin molecule required for its action in the rosette inhibition test of a substance to find out the chemicals.
Instead this study have pin- pointed cysteine 72 as being of particular importance and that this residue must be reduced... [continues]
AMONG FILIPINO COLLEGE STUDENTS
A Research Proposal
Presented to
The Faculty of the College of Nursing
Our Lady of Fatima University
In the Fulfillment of the
Requirements of the Degree
Bachelor of Science in Nursing
by:
Ariel A. Abeleda
Laarnie S. Chan
Cristy A. Laureta
Joan R. Mapilis
Kierwin P. Mariano
Ralph Roger R. Nicolas
Justin Jake C. Ortega
Maridel P. Placido
Archie P. Santos
BSN 3Y3-11
CHAPTER 1
The Problem and It’s Background
Introduction
The first and known systemic sign of the existence of a variable embryo prior to implantation is the presence of a lymphocyte modifying activity which is detectable in maternal serum within hours of fertilization. The study of this so called “early pregnancy factor” activity has generated considerable interest in the field of reproductive biology due not only to the potential to develop, extremely early methods of pregnancy detection but also to monitor embryo viability prior to implantation.
An objective assessment of the basic observation can only be interpreted as “EPF” activity expression being due to the action of a complex system. As such a new paradigm has been proposed by Clarke to explain the capacity of pregnancy. Briefly, it has been proposed that all blood serum contain inherently active low molecular weight moieties, and in addition possess the capacity to stimulate the production of even more when applied to the lymphocytes to the rosette inhibition assay.
The present studies extend this model by defining the role of thioredoxin in the “EPF” phenomenon with site directed the production genetic change studies determining the molecular features of the thioredoxin molecule required for its action in the rosette inhibition test of a substance to find out the chemicals.
Instead this study have pin- pointed cysteine 72 as being of particular importance and that this residue must be reduced... [continues]
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