It is difficult to attribute a particular clinical syndrome to a particular drug type. …show more content…
Patients are usually young, and often remarkably young for the type of pathology presenting (for example, stroke). People with drug addictions usually present acute, with severe neurological deficits, and often have been waiting for an extraordinary time before seeking medical attention because of the additions itself, socioeconomical, and/or legal implications. The health history from the patient, relatives, or friends is often inconsistent and unreliable, or misleading. Drug misuse is usually not volunteered, but is generally admitted if directly questioned. Multiple pathologies are possible and common. It is important not to jump to rare neurological diagnosis, since a large majority of people with drug additions will be given common and mundane diagnosis and treatment with a good physical …show more content…
They usually occur in the first few hours after ingestion in a chronic heavy abuser, presenting with headache, an evolving focal deficit and impaired conscious level. Hemorrhages are the most common type of stroke, but even in these patients transient ischemia attack like episodes may have occurred previously. Infarction may also occur, particularly with crystal methamphetamine, which is the smoked form. Angiography may be normal but amphetamines may also be associated with beading of large arteries, or focal narrowing of arteries. Especially when used chronically and intravenously, amphetamines are the drugs most commonly associated with arrhythmias. This may be an acute hypersensitivity reaction, possibly caused by contaminants. People who abuse cocaine and amphetamines are less likely to present as clear cut strokes cases. They seem to have a more diffused neurological presentation, often with a subacute progressive time course while hospitalized, including headache, encephalopathy and/or clinical presentation of bilateral hemorrhages. Amphetamine ‘‘look-alikes’’ like ephedrine and pseudoephedrine share many of the same potential effects of amphetamines, particularly those involving the cerebral circulation. Although the risks of adverse effects occurring are less, this may be outweighed by the more widespread use and availability of these drugs in the