Preview

Neurological Disease Hd

Better Essays
Open Document
Open Document
1090 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Neurological Disease Hd
Robbie Shell
Mr. Pletcher
Anatomy Honors
11/26/12
Neurological Disorder There are many neurological diseases and disorders that affect the nation’s population. Many go unnoticed while others have severe symptoms. One such disease is a neurological disorder called Huntington’s disease or HD. Huntington’s Disease is a neurological disorder that affects the brain by forming abnormal brain cells that do not function correctly this disease is incurable and how it spreads is unknown. Huntington’s disease has been found in most races and becomes evident in mid to late forties. Neurologic diseases are disorders that affect the brain, spinal cord or nerves in your body. Damage to your nervous system can cause you to have trouble doing things like moving, speaking, swallowing, breathing or learning. You can also have problems with your memory, senses or mood. Huntington’s Disease is caused by a genetic defect on Chromosome 4. The defect causes a part of your DNA to produce abnormal brain cells killing the good ones in their place. As the gene is passed down the number of repeats tends to get larger. With more and more repeats the patient has a greater chance to develop it earlier. There are two forms of Huntington 's Disease. The most common is adult-onset Huntington 's disease. Persons with this form usually develop symptoms in their mid-30s and 40s. Huntington 's Disease accounts for a small number of cases that begin in childhood or adolescence. Huntington’s disease affects the nerve cells in the brain damaging them, causing various parts of the brain to deteriorate. The disease affects movement and behavior while many simple tasks such as walking, thinking, reasoning and talking are gradually taken to such a point that they eventually become entirely reliant on other people for their care as they become more and more impaired from this disease. If a parent has Huntington 's disease, the child has a 50% chance of getting the gene for the disease. And if they



Cited: * Genetic Science Learning Center. "Huntington 's Disease." Learn. Genetics 29 November 2012 <http://learn.genetics.utah.edu/content/disorders/whataregd/hunt/> * Arthur Schoenstadt, MD. “Huntington’s Disease Statistics.” Emed Tv 29 November 2012 < www.google.com/url?sa=f&rct=j&url=http://nervous-system.emedtv.com/huntington 's-disease/huntington 's-disease-statistics.html&q=percentage+of+people+who+have+huntington 's+disease&ei=v_G3UK6jLo3s8gTLmoCACg&usg=AFQjCNEE-m2demjYJ4WCglH8B1dHZ6wMJQ> * “Effects Of Huntington’s Disease” ManchesterNeroPhysio 29 November 2012 <http://www.manchesterneurophysio.co.uk/huntingtons/effects.html> * “Huntington’s Disease Society of America” Juvenile Huntington 's Disease 29 November 2012 < http://www.hdsa.org/living-with-huntingtons/family-care/juvenile-hd/index.html> * Mayo Clinic Staff. “ Treatments and drugs” Mayo Clinic 29 November 2012 http://www.mayoclinic.com/health/huntingtons-disease/DS00401/DSECTION=treatments-and-drugs

You May Also Find These Documents Helpful

  • Good Essays

    A diagnosis of Huntington’s disease can be very distressing for a patient and their family to receive as it has many effects.…

    • 125 Words
    • 1 Page
    Good Essays
  • Satisfactory Essays

    Huntington’s disease is inherited as a dominant gene, because it is passed on with each generation.…

    • 468 Words
    • 2 Pages
    Satisfactory Essays
  • Powerful Essays

    Huntington’s is a genetic and autosomal dominant inherited disease; meaning that it is not affected 23rd chromosome also known as the sex chromosome. This indicates that if one has any parent with Huntington’s (female or male), they have a 50% chance of contracting the disease which can be seen in Figure 1. (Collins, n.d) . An irregular expansion of a reciprocated area of the DNA sequences of the gene is the result of the Huntingtin gene. That particular area encodes the amino acid glutamine. (healthtree, n.d) In a normal, healthy person; one has a string of 9 to 39 glutamines. But due to the irregular expansion of the Huntingtin gene, people with Huntington 's have 36 - 121 glutamines; well above the normal range. Due to the extreme size of this area, it makes the Huntingtin protein more unstable and turns the area into an abnormal shape. (healthtree, n.d)Though we know the genetics behind it, it is still a mystery why this Huntingtin protein causing neuron death in the striatum, the substantia nigra and the hypothalamus of the brain which can be seen in Figure 2 (look at yellow boxes). (healthtree, n.d)Due to the nature of the disease being…

    • 1541 Words
    • 7 Pages
    Powerful Essays
  • Good Essays

    Lou Gehrigs Disease

    • 868 Words
    • 3 Pages

    Amyotrophic lateral sclerosis; Motor neuron disorders are far from rare: Parkinson’s disease, multiple sclerosis, and a variety of lesser diseases all come under that heading. A disease of the nerve cells in the brain and spinal cord that controls voluntary muscle movement. ALS, Lou Gehrig’s disease, Amyotrophic lateral sclerosis are all names for this horrid disease. The symptoms; Difficulty breathing, sudden paralysis. Treatment is slim to none but there are known medications to help subside the pain that may be felt. The Cause is unknown, doctors are unsure if this disease is genetic or cause by one’s self.…

    • 868 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    P2 Unit 1

    • 6811 Words
    • 28 Pages

    Huntington’s disease affects the way a person moves around. The disease destroys cells in the basal ganglia, the part of the brain that controls movement, emotion, and cognitive ability. Cystic Fibrosis is a hereditary disease of the mucus, saliva and sweat glands. It affects organs like; lungs, pancreas, liver and intestines.…

    • 6811 Words
    • 28 Pages
    Powerful Essays
  • Powerful Essays

    The human body is made of different organs that collaborate to control the normal functioning of the brain. If this region organ is, affected poor functioning of the body can be experienced since the brain controls all other organs. Disorders of the brain may develop due to physical injuries to the head, accidents, hereditary or due to some harmful environmental conditions. Failure of communication of the nerves and neurons in the brain can result to development of a brain disorder. Most brain disorders have no cure and they have adverse effects to the individual to an extent that they may be everlasting…

    • 3438 Words
    • 14 Pages
    Powerful Essays
  • Good Essays

    Neurodegenerative diseases is a common cause of dementia which means that the brain cells known at the neurons either are degenerating therefore the neuron die off quicker than that of the neurons of a normal aging processes. This will lead to a more decline in the persons mental health such as memory, language and sometimes their physical abilities all depending on which area of the brain is infected. These neurodegenerative diseases are known to us as Alzheimer’s, fronto-temporal dementia, and Lewy bodies are where over time a build up of abnormal protein deposits in the brain cause the gradual change and damage to the neurons which will cause the shrinkage of the brain. Dementia is anything which affects the brain and the loss of function of the brain in such a way that the things we normally take for granted for e.g. our ability to remember things such as time, date, events, to place ourselves in a location to use words, to use language all of these things begin to disappear.…

    • 616 Words
    • 2 Pages
    Good Essays
  • Good Essays

    It is caused by getting passed down from parents. HD results from genetically programmed degeneration of nerve cells, called neurons, in certain…

    • 764 Words
    • 4 Pages
    Good Essays
  • Satisfactory Essays

    Alzheimers - is a physical disease that affects the brain. There are nore than half a million people in the UK with the disease. Alzheimers is progress when a build up of proteins in the brain lead to a loss of connection between the nerve cells. This itself causes the death of these nerve cells and the loss of brain tissue. People with alzheimers also suffer from a shortage of chemicals in their brain. Thesse chemicals are used to transmit signals around the brain. Where there is a shortage the signals are not transmitted effectively. This causes the person to have confusion over places and time and also issues with thinking and memory loss.…

    • 5459 Words
    • 13 Pages
    Satisfactory Essays
  • Better Essays

    Although characterized as an “adult on-set” disease, it can affect children as well (Medterms, 1998). Huntington’s is a genetic disorder that main affects people in their 40’s and 50’s (Team C, 2011). I mainly affects the brain which leads to a gradual loss of control of movement along with memory loss and a loss of mental ability (Team C, 2011). I suppose you could say it is essentially a breakdown of the brain and the functions that are accompanied with it (Team C, 2011). With Huntington’s disease comes certain personality changes and depression along with some other mental illnesses (Team C, 2011). As of now there is no known cure but there have been a few case studies researching the possibility of a cure (Team C, 2011). Huntington’s disease has a pattern known as “autosomal dominance” (Team C, 2011). Autosomes Are the chromosomes inside the cells of the body aside from the sex chromosomes (Team C, 2011). This is where our body’s genetic information is stored and located (Team C, 2011). The genetic abnormality that is normally associated with Huntington’s disease is located on the fourth chromosome and the three bases arranged along the chromosome happen in a repeated sequence (Team C, 2011). An excess amount of the repeats leads to Huntington’s disease (Team C, 2011). Any more than 35 reps of this particular sequence is often attributed to Huntington’s but…

    • 1220 Words
    • 5 Pages
    Better Essays
  • Satisfactory Essays

    Alzheimers Disease Anne Harrison Description ● Alzheimer 's disease is a progressive, degenerative disorder that affects the brain 's nerve cells, or neurons, ending up in loss of memory, thinking and language skills, and behavioral changes. Cause ● Plaques: clumps of a protein that damage and destroy brain cells. ● Tangles: Strands that ruin cell transport made of proteins. Most Affected ● ● ● Age: 65-80 is the usual age Sex: More women are affected than men (Alzheimer.org)…

    • 483 Words
    • 2 Pages
    Satisfactory Essays
  • Better Essays

    Alzheimer's is the most common form of dementia. According to George Krucik, M.D., Alzheimer's accounts for 60 to 80 percent of dementia cases. Alzheimer's is one of many forms of dementia. Other types of dementia include: Vascular Dementia, Mixed Dementia, Parkinson's Disease, Normal Pressure Hydrocephalus, Lewy Body Disease, and Huntington's Disease. Vascular Dementia is the second most common form of dementia. Some symptoms include impaired judgement or ability to plan steps needed to complete a task. Mixed Dementia is a condition in which characteristics of more than one type of dementia occurs simultaneously (Alzheimer's Association). Parkinson's Disease may cause tremors and stiffness. This is a disorder of the central nervous system that affect movement. Normal Pressure Hydrocephalus affects walking, memory, and the ability to control urination. Lewy Body Disease is also known as "The Nightmare Dementia". This disease causes intense hallucinations that replicate many fears. For example, one with Lewy Body Disease may imagine spiders or snakes crawling all over the room. Next is Huntington's Disease, this is a progressive brain disorder caused by a single defective gene on Chromosome Four. Last is Vascular Dementia. Vascular Dementia is a form of brain damage caused by multiple strokes. This disease may last for years or it may be…

    • 875 Words
    • 4 Pages
    Better Essays
  • Good Essays

    Neuron Disorders

    • 537 Words
    • 3 Pages

    While neuron disorders are debilitating diseases, scientists are researching promising new cures. This research ranges from the crosstalk between motor and sensory neurons, to the morphing of skin cells, and the function of the CLP1 gene and its role in certain diseases.…

    • 537 Words
    • 3 Pages
    Good Essays
  • Better Essays

    Huntington’s Disease, previously known as Huntington’s chorea, is a long term brain disorder that eventually leads to uncontrolled movement, problems with emotions, loss of cognitive abilities such as memorization, increased involuntary movements, behavioral symptoms, and degeneration of nerve cells in the brain(1). This disease has been recognized as a disorder for hundreds of years, but however, only recently a cause was instituted to explain the effects. During the eighteenth and nineteenth centuries, gene heredity was poorly understood as people who had the gene coding for the disease, died before many symptoms could appear. Huntington's Disease was first identified as an…

    • 973 Words
    • 4 Pages
    Better Essays
  • Good Essays

    The striatum in the brain is believed to play a large factor in the cause of the symptoms of Huntington’s disease. Its function is to process all of the signals within the neocortex and then pass them to other parts of the basal ganglia and frontal lobes. The parts of the brain that the striatum sends its information to are known for playing a large role in the planning and execution of a person’s bodily movement. Huntington’s disease seems to disrupt the striatum’s pathway in sending its messages, which then interferes with the parts of the brain that control movement. This pathway disruption is what causes the loss of muscle control for those who suffer from the disease. As a person is first affected, the chorea starts off as minor but as the disease progresses more damage is done to the brain, which results in an increase in the severity of symptoms. This is believed to be the reason behind eighty percent of brains belonging to those who have died of Huntington’s disease having significant atrophy to their frontal lobes. Along with a loss of frontal lobe tissue, this disease also causes a loss of striatal tissue, a noticeable amount of one hundred percent of all Huntington’s disease brains examined. Expectedly, on average a brain that has gone through the symptoms of Huntington’s disease is on average smaller than a normal unaffected…

    • 1026 Words
    • 5 Pages
    Good Essays