Preview

Multidrug Resistant Tuberculosis Research Paper

Good Essays
Open Document
Open Document
886 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Multidrug Resistant Tuberculosis Research Paper
Multidrug Resistant Tuberculosis (MDR TB)
TB has plagued the world since the beginning of cattle domestication in 4000bc. The man and beast interaction allowed M. bovis (mad cow disease) to develop properties allowing for survival within their new hosts. This new class of bacteria was deemed. The evolution of the TB causing bacteria did not stop there. The newest mutation of this bacterium is MDR TB, or multidrug resistant tuberculosis. The three main causes that have allowed TB to progressively develop into this multidrug resistant strain are progression, transmission, and over-population.
One cause of MDR Tuberculosis is its progression due to unawareness and the overwhelming number infections in third world countries. M. tuberculosis is an
…show more content…
Transmission occurs primarily from non-compliance of the drug-therapy and inaccessibility of proper air-borne isolation techniques. Correctly quarantining a known infected patient is imperative, particularly until the strain of TB has been determined as well as until treatment has been launched. To clarify how MDR TB is inadvertently transmitted WHO explains, “Treatment for MDR TB involves drug therapy over many months or years. Despite the longer course of treatment the cure rate decreases from over 90 percent for nonresistant strains of TB to 50 percent or less for MDR TB.” (2012). Laid out by the American Lung Association (2013), “A strain of MDR TB originally develops when a case of drug-susceptible tuberculosis is improperly or incompletely treated. This occurs when a physician does not prescribe proper treatment regimens or when a patient is unable to adhere to therapy. Improper treatment allows individual TB bacilli that have natural resistance to a drug to multiply.” When a patient has no signs or symptoms of latent tuberculosis, the consequences may be life threatening, not only to the patient, but also to all the people that are around

You May Also Find These Documents Helpful

  • Satisfactory Essays

    Tuberculosis is caused by a bacterium called Mycobacterium tuberculosis. The disease can affect the lungs and can cause other problems in some parts of the body such as the brain, the kidney, and the spine. In 2013 Tuberculosis killed 9 million people…

    • 306 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    2. For some time, Russian prisons have been running on drastically reduced budgets. As a result, when inmates contracted tuberculosis (TB is caused by an infection of the lungs by a particular bacteria species), treatment with antibiotics was often halted before all TB bacteria had been killed by the antibiotics in an infected prisoner. It is now observed that strains of antibiotic resistant TB have appeared in the Russian prison population. Such strains have now reached the United States when freed prisoners have emigrated. What might provide a scientifically valid explanation for the appearance of antibiotic-resistant TB?…

    • 1776 Words
    • 6 Pages
    Good Essays
  • Good Essays

    Ap Biology Unit 9 Essay

    • 659 Words
    • 3 Pages

    “More than a quarter of multi-drug resistant tuberculosis (MDR-TB) strains isolated in a national survey in Swaziland carry a mutation that is undetectable by the advanced rapid molecular diagnostic tests currently in widespread use,”(MSF, 2015, p.1).…

    • 659 Words
    • 3 Pages
    Good Essays
  • Better Essays

    Throughout the history of mankind, Tuberculosis (TB) has claimed numerous victims. During the 18th and 19th century, TB became an epidemic in North America and Europe, gaining the cognomen, “Captain Among these Men of Death.’’ Therefore, scientists have to find the pathogenesis of this disease to enhance their understanding of the epidemic (Daniel, 2006). Tuberculosis is categorized as an infectious disease in mankind’s history. Statistics show 1 out of 7 of all humans die from tuberculosis (Koch, 1882). In the United States, almost 20,000 cases of tuberculosis are diagnosed yearly, and 9 million worldwide (Miller et al, 2000). The nature of TB has been studied by many,…

    • 1662 Words
    • 7 Pages
    Better Essays
  • Good Essays

    Mycobacterium tuberculosis is the bacterium that causes tuberculosis. Also known as TB, tuberculosis bacteria attacks the lungs in most cases but can attack other parts of the body. If not treated properly tuberculosis can be fatal. Tuberculosis is an airborne bacterium spread from person to person. According to the CDC, Center for Disease Control, “TB bacteria are put into the air when a person with TB disease of the lungs or throat coughs, sneezes, speaks, or sings”("Tuberculosis facts," 2012, p. 1). Tuberculosis cannot be spread by touching an infected person, sharing food or drink, sharing toothbrushes, or from kissing. Transmission has not changed throughout the centuries.…

    • 1065 Words
    • 5 Pages
    Good Essays
  • Good Essays

    However, in 2014, approximately 480,000 people developed multidrug resistant TB (MDR-TB) in the world. Thus, treating with the right TB medications is vital for patients with active or latent TB infection. Patients who refuse TB treatment against medical advice are endangering the exposure of the infection to the public thus needs to be detained or isolated.…

    • 557 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    The Power of L.O.L

    • 268 Words
    • 2 Pages

    8. Explain the events that led to the evolution of antibiotic-resistant TB in the prisoner.…

    • 268 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    Article Case Law

    • 930 Words
    • 4 Pages

    The challenge of controlling TB in its traditional and new multidrug-resistant forms requires public health agencies at the federal, tribal, state, and local levels to develop and apply new tools. Among these tools is the use of law in support of efforts to effectively control cases of TB. In May of 2005, the World Health Organization initiated for Vaccine Research. This research was arranged to develop into a meeting of regulators, investigators, and clinicians from different countries that are in the process of developing or countries that have already been developed. Their main cause was to initiate tuberculosis vaccine regulation and research. The discussion that was made in this assembly was of the regulatory challenges for testing and introducing investigative TB vaccines into country where the disease is widespread.…

    • 930 Words
    • 4 Pages
    Good Essays
  • Powerful Essays

    Health Canada. (1998). Proceedings of the national consensus conference on tuberculosis. Canadian Commission Disease Report; 24S2: 1-24.…

    • 7025 Words
    • 29 Pages
    Powerful Essays
  • Good Essays

    Finally, doctors discovered that the combination of drugs, which included Streptomycin, Isoniazid, Para-aminosalicylic, actually improved the conditions of tuberculosis and also revolutionized the level of treatment available. Despite the definite improvements in tuberculosis treatment, a resurgence of tuberculosis began in the 1990’s. With even more drugs such as Rifampin and Ethambutol being available as a result of the advancement of modern medicine, treatment became a quicker yet extremely variable process, since many factors weigh in to the success of a form of treatment, “The exact drugs and length of treatment depend on your age, overall health, possible drug resistance, the form of TB and the infection’s location in the body” (Staff 1). These effects all display the variety and wide range that demonstrate the large importance of the treatment of tuberculosis. Finally, the treatment of tuberculosis fundamentally impacted the importance of the awful infection throughout the Victorian Era and…

    • 308 Words
    • 2 Pages
    Good Essays
  • Better Essays

    Epidemiology Paper

    • 1265 Words
    • 4 Pages

    References: Center for Diseases Control and Prevention. Basic TB facts (2012). Retrieved on July 27, 2014…

    • 1265 Words
    • 4 Pages
    Better Essays
  • Better Essays

    Tuberculosis(TB) is a air bourn infectious disease which is caused by Mycobacterium Tuberculosis. People who are living in poor socioeconomic background and who are living in medically underserved communities are more prone to this deadly , but preventable and curable disease. This disease continue to be as an indicator of poverty and low socio-economic background. Most of the time people affected with this deadly disease are undiagnosed early and affected with malnutrition or immunologically compromised. Tuberculosis can affect several organs of human body, including brain, bones, kidney. Mostly it affects the lungs and spreads through the infected droplets of saliva when the infected person talks, coughs or sneezes. According WHO fact sheets, “Tuberculosis is next to HIV/AIDS in causing death of human worldwide. In 2012, 8.6 million people got sick with TB and 1.3 million people died due to TB infection”(WHO,…

    • 1560 Words
    • 7 Pages
    Better Essays
  • Good Essays

    Communicable Disease Paper Tuberculosis Communicable diseases rely on fluid exchange, contaminated substance, or close contact to travel from an infected carrier to a healthy individual. Many people have never heard of a disease called tuberculosis (TB) or not fully aware how serious this disease really is. I will briefly summarize the research that was conducted on tuberculosis by describing the disease in details and discussing efforts to control it, indentify environmental factors related to tuberculosis, and explain the influence of lifestyles, socioeconomic status, as well as disease management. I will also briefly describe what public health departments are doing to reduce the threat, and include data, evidence, and plan to ensure quality health. Tuberculosis (TB) is a disease that is caused by a bacterium called mycobacterium tuberculosis. The bacteria usually attack the lungs, but TB bacteria can also attack any part of the body such as the kidney, spine, and brain. TB is spread through the air from person to person because this bacteria is put into the air when a person that is diagnosed with it in the lungs, coughs, speaks, sneezes, or sings. People that have tuberculosis should be treated immediately because it can be fatal and they are putting people nearby at risk of becoming effected. Tuberculosis can be controlled if there are appropriate actions taking by seeing some type of health care professional that is able to diagnosis, treat, and monitor the disease. Crowding in homes, homeless shelters and prisons are has been observed to be the highest risk in tuberculosis among persons of contact. Children that leave in a crowded house with effected individuals have a greater increase degree of shared airspace are more exposed and it increases limited air movement. Crowded places like prisons have been reported to at a higher risk than any type of civilian population (World Health Organization, 2014). TB can sometimes provide late symptoms or…

    • 911 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    Pulmonary tuberculosis also referred to as (TB) is a contagious bacterial infection that generally affects the lungs; however TB can attack other organs in the body such as the brain, spine, and kidney. Tb can most often be treated however, if it is not properly treated, the disease can result in fatality. It is an airborne disease commonly but can also spread via person to person contracted in hospitals, nursing homes, daycares and other health care facilities. The bacteria within tuberculosis are spread with in the air when the person infected with TB sneezes, coughs, sings, or speaks. Individuals that are close to those infected may become infected after breathing in this bacterium. (C.D.C. 2014)…

    • 213 Words
    • 1 Page
    Satisfactory Essays
  • Powerful Essays

    Tuberculosis

    • 2267 Words
    • 10 Pages

    Before the 20th century, there was little hope of survival for patients diagnosed with tuberculosis. The disease was considered impossible to fight and the only course of remedy was staying healthy by managing a healthy diet and getting plenty of rest (Goldberg et al., 2012). In 1921, advancements in scientific research led to the development of the first vaccine, known as Mycobacterium bovis bacillus Calmette-Guerin (BCG) (Lienhardt et al., 2012). The discovery of streptomycin (SM) along with paraaminosalicylic acid (PAS) led to a major breakthrough in tuberculosis control known as combination therapy (Goldberg et al., 2012). By combining the medicinal affects of both drugs, tuberculosis finally had an effective method of recovery. Isoniazid was added to the multi-therapy approach after it was discovered in 1951 and together the three drugs cured infected patients within 18-24 months (Lienhardt et al., 2012). Over the years this therapy was altered with the addition and deletion of various drugs and ultimately became the cardinal method of TB control (Goldberg et al., 2012). PAS was replaced with ethambutol in the 1960s, rifampicin was added in the 1970s, and streptomycin was substituted by pyrazinamide in the 1980s (Lienhardt et al., 2012). Today this serious infection is treated with a method known as DOTS- directly observed therapy short course (Weltman et al., 2012). “DOTS includes finding as many highly infected patients with TB as possible, initiating effective treatment, directly observing drug ingestion to ensure adherence, and standardized monitoring, evaluation, and reporting” (Weltman et al., 2012). The drugs utilized in tuberculosis control have brought researchers and doctors closer to diminishing the deaths caused by this endemic.…

    • 2267 Words
    • 10 Pages
    Powerful Essays

Related Topics